SPEC – Handbook of Clinical Neurology, Volume 144, Huntington Disease, 12-Month Access, eBook: Handbook of Clinical Neurology, cartea 144
Andrew S. Feigin, Karen E. Andersonen Limba Engleză Hardback – 24 oct 2017
This book also addresses behavioral and cognitive symptoms, brain imaging, and family dynamics and therapeutic alliances in working with individuals affected by HD. Clinical trials are covered extensively, including design considerations for therapeutic studies. The devastating nature of Huntington’s disease is well appreciated throughout the neuroscience, neurology, and psychiatric communities, and a great amount of basic and clinical research is currently taking place. However, much of that occurs in isolated research silos, and it is critical that an interdisciplinary resource be developed to provide in depth information to enhance communication and collaboration. This volume in the Handbook of Clinical Neurology series is that resource.
- Includes coverage of both basic science and clinical aspects of the disease, as well as treatment, experimental therapeutics, and biomarkers
- Provides an essential resource for the non-neurologist, including necessary background for understanding the disease before making a more detailed study proposal
- Provides an interdisciplinary approach that can be applied in everyday clinic and research efforts
- Features chapters edited by leaders in the field around the globe—the broadest expert coverage available
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Specificații
ISBN-13: 9780128018934
ISBN-10: 0128018933
Pagini: 312
Dimensiuni: 195 x 260 mm
Greutate: 0.95 kg
Editura: ELSEVIER SCIENCE
Seria Handbook of Clinical Neurology
ISBN-10: 0128018933
Pagini: 312
Dimensiuni: 195 x 260 mm
Greutate: 0.95 kg
Editura: ELSEVIER SCIENCE
Seria Handbook of Clinical Neurology
Public țintă
Researchers, clinicians and advanced students in the fields of neurology, psychiatry, neuropsychology, genetics and clinical neuroscienceCuprins
Section 1 Basic Science
1. Genetics of Huntington disease
2. Mechanisms underlying neurodegeneration in Huntington disease: Applications to novel disease-modifying therapies
Section 2 Clinical Aspects
3. Epidemiology of Huntington disease
4. Statistical modelling of Huntington disease onset
5. The diagnosis and natural history of Huntington disease
6. Preclinical cognitive and behavioral changes in Huntington disease
7. Preclinical motor manifestations of Huntington disease
8. The highly anxious individual presenting for Huntington disease predictive genetic testing: the psychiatrist’s role in assessment and counseling
9. Reproductive options for Huntington disease families
10. Genetic testing for Huntington disease
Section 3 Treatment of Huntington Disease
11. Medical treatment of behavioral manifestations of Huntington disease
12. Medical management of motor manifestations of Huntington disease
13. The role of rehabilitation therapy in Huntington disease
14. Contemporary health care for Huntington disease
15. The impact of Huntington disease on young people
16. Making a measurable difference in advanced Huntington disease care
Section 4 Experimental Therapeutics
17. New symptomatic therapies for Huntington disease
18. Motor outcome measures in Huntington disease clinical trials
19. Cognitive outcome measures in Huntington disease clinical drug trials
Section 5 Biomarkers
20. Structural imaging in premanifest and manifest Huntington disease
21. Functional imaging in Huntington disease
1. Genetics of Huntington disease
2. Mechanisms underlying neurodegeneration in Huntington disease: Applications to novel disease-modifying therapies
Section 2 Clinical Aspects
3. Epidemiology of Huntington disease
4. Statistical modelling of Huntington disease onset
5. The diagnosis and natural history of Huntington disease
6. Preclinical cognitive and behavioral changes in Huntington disease
7. Preclinical motor manifestations of Huntington disease
8. The highly anxious individual presenting for Huntington disease predictive genetic testing: the psychiatrist’s role in assessment and counseling
9. Reproductive options for Huntington disease families
10. Genetic testing for Huntington disease
Section 3 Treatment of Huntington Disease
11. Medical treatment of behavioral manifestations of Huntington disease
12. Medical management of motor manifestations of Huntington disease
13. The role of rehabilitation therapy in Huntington disease
14. Contemporary health care for Huntington disease
15. The impact of Huntington disease on young people
16. Making a measurable difference in advanced Huntington disease care
Section 4 Experimental Therapeutics
17. New symptomatic therapies for Huntington disease
18. Motor outcome measures in Huntington disease clinical trials
19. Cognitive outcome measures in Huntington disease clinical drug trials
Section 5 Biomarkers
20. Structural imaging in premanifest and manifest Huntington disease
21. Functional imaging in Huntington disease