Steroids in the Laboratory and Clinical Practice de John William Honour

Steroids in the Laboratory and Clinical Practice

John William Honour

Steroids in the Laboratory and Clinical Practice covers both basic chemistry and therapeutic application of steroids in a single source. The comprehensive reference addresses the specificity of steroid determinations to clarify confusion arising from the laboratory results. The book covers important advancements in the field and is a valuable addition in the literature addressing all existing knowledge gaps. This is a must have reference for pathologists, laboratorians, endocrinologists, analytical/clinical chemists and biochemists.

Addresses the normal production of steroids and concentrations found in biological fluids and tissues
Presents the changes in steroid concentrations at life events as reference points for clinical investigations
Reviews the genetic disorders of steroids in relation to specific enzyme changes and clinical presentation

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"The planning of this book and the Sections are laid out in a systematic, convenient way and can be followed very easily by the reader. Each Section meticulously covers the chemistry, synthesis, regulation of their biosynthesis, measurement in blood and tissues, their physiological properties, their metabolism and clearance, their quantitative analysis and clinical usefulness in the various disease states. This has been accomplished with extraordinary insight as to what needs to be known by modern investigators, whether investigational or related to clinical disease outcomes.
This book is illuminated by many Tables and Figures, again extremely well thought out and highly useful, taking into account the needs of the reader. What is truly remarkable is the timing of such a well written book. As an example, the coverage of the conjugation and de-conjugation, of steroids and steroid hormone metaboites, including DHEA-S and DHEA, has been carefully considered and is so relevant; as are so many of the sections on mechanisms of steroid hormone action. This book, Steroids in the Laboratory and Clinical Practice, is not only timely but absolutely needed as a new era of interest in the function of steroids is unveiled. This seminal textbook will be used as a guide for the emerging field of steroids, steroid hormones and their metabolites, once considered inert, but now all playing important pivotal functional roles." --David J Morris D.Phil., Emeritus Professor of Pathology and Laboratory Medicine

"…a comprehensive reference book that addresses the specificity of steroid determinations that can clarify confusion clinicians face with abnormal laboratory results….includes all the information needed to understand key concepts of steroid synthesis, action, and biological effects.…covers both basic and analytical applications of steroids to medicine in one source…..this book should be the “go-to” book for clinicians, researchers, pathologists, laboratorians, analytical biochemists, and students…” --Derek Bagley, Endocrine News

*5 stars* "...a comprehensive reference for understanding the structure and function of each steroid in the human body... [and] would greatly benefit anyone who is interested in the field of steroid metabolism, disorders, or pharmacology... The organization of this book is quite impressive as three separate sections cover every feature of a steroid's existence. The diagram, tables and indices are very clear and useful... [It] intends to teach readers about a complicated topic in an organized, easily digestible, and actually enjoyable fashion." --©Doody’s Review Service, 2024, Prathayini Subarajan, MD (Loyola University Medical Center)

Steroids in the Laboratory and Clinical Practice

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Steroids in the Laboratory and Clinical Practice

Preț: 837.13 lei

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Cuprins

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Preț: 837^.13 lei