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Synthesis and Characterization of Glycosides

Autor Marco Brito-Arias
en Limba Engleză Paperback – 30 mai 2018
This second edition is a short and comprehensive study on the best known approaches for preparing the main types of glycosides. It covers synthetic pathways of challenging glycosides known as antiviral or antineoplastic drugs, and synthetic substrates used for enzymatic detection, including those used for detection of gene markers in plant biotechnology. The author pays special attention to the structural characterization of glycosides and provides the basic tools for the structural assignment through NMR, X-Ray and mass spectra techniques. The book also covers strategies for preparation of antiviral and antineoplastic drugs included in a drug design course.
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Specificații

ISBN-13: 9783319812519
ISBN-10: 3319812513
Ilustrații: XVII, 422 p. 487 illus., 75 illus. in color.
Dimensiuni: 155 x 235 mm
Greutate: 0.61 kg
Ediția:Softcover reprint of the original 2nd ed. 2016
Editura: Springer International Publishing
Colecția Springer
Locul publicării:Cham, Switzerland

Cuprins

Introduction.- O-Glycoside Formation.- N-glycosides.- Nucleotide Mimetics.- C-glycosides.- Glycoconjugates.- Hydrolysis of Glycosides.- Nuclear Magnetic Resonance of Glycosides.- X-Ray Diffraction of Glycosides.- Mass Spectrometry of Glycosides.- Docking studies of Glycosides.- Index.

Notă biografică

Marco Brito-Arias is at the National Polytechnic Institute in Mexico.

Textul de pe ultima copertă

This second edition is a short and comprehensive study on the best known approaches for preparing the main types of glycosides. It covers synthetic pathways of challenging glycosides known as antiviral or antineoplastic drugs, and synthetic substrates used for enzymatic detection, including those used for detection of gene markers in plant biotechnology. The author pays special attention to the structural characterization of glycosides and provides the basic tools for the structural assignment through NMR, X-Ray and mass spectra techniques. The book also covers strategies for preparation of antiviral and antineoplastic drugs included in a drug design course.

Caracteristici

Improves on the first edition by incorporating updated information about methods for preparing O-, C- and N-glycosides Second edition includes new material on docking studies of glycosides Contains basic tools for newcomers to the field and more substantial explanations for the better versed Examines the different types of glycosides and their applications in health, food and biotechnological sectors Includes supplementary material: sn.pub/extras

Recenzii

From the reviews:
"Brito-Arias … provides an overview of the structures and synthetic preparations of O-, N-, and C-glycosides, as well as discussion of the conformational features and biological function of selected examples. … The organization of the book provides a ready resource for researchers seeking information. Indeed, the references to published synthetic methodology or analytical data included at the end of each chapter will be useful for researchers seeking additional information or details on a specific topic. … Summing Up: Recommended. Graduate students through professionals." (P. W. Baures, CHOICE, Vol. 44 (11), July, 2007)