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The Chemistry and Biology of Benz[a]anthracenes: Cambridge Monographs on Cancer Research

Autor M. S. Newman, B. Tierney, S. Veeraraghavan
en Limba Engleză Paperback – 3 iun 2009
First published in 1988, this volume surveys the chemical synthesis and biological activity of the benz[a]anthracenes. These compounds occur in smoke and mineral oils and a few have been shown to be potent carcinogens. This volume was the first to review, systematically and in depth, the organic synthesis of these compounds as well as their metablolism, interactions with nucleic acids and protein, mutagenicity and carcinogenicity. Such studies have important implications in determining mechanism and specificity of chemically induced carcinogenesis.
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Specificații

ISBN-13: 9780521105897
ISBN-10: 0521105897
Pagini: 244
Dimensiuni: 152 x 229 x 14 mm
Greutate: 0.36 kg
Editura: Cambridge University Press
Colecția Cambridge University Press
Seria Cambridge Monographs on Cancer Research

Locul publicării:Cambridge, United Kingdom

Cuprins

Part I. Chemistry: 1. Synthetic routes from benzenes and naphthalenes; 2. Synthetic routes from anthracenes (A-ring formation); 3. Synthetic routes from anthracenes (D-ring formation); Part II. Biology: 8. Metabolism; 9. DNA, RNA and protein interactions; 10. Mutagenicity; 11. Carciogenicity; References; Index.

Descriere

First published in 1988, this volume surveys the chemical synthesis and biological activity of the benz[a]anthracenes.