The Consequences of Chromosome Imbalance: Principles, Mechanisms, and Models: Developmental and Cell Biology Series, cartea 18
Autor Charles J. Epsteinen Limba Engleză Paperback – 25 iul 2007
Toate formatele și edițiile | Preț | Express |
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Paperback (1) | 433.25 lei 43-57 zile | |
Cambridge University Press – 25 iul 2007 | 433.25 lei 43-57 zile | |
Hardback (1) | 1123.62 lei 43-57 zile | |
Cambridge University Press – 30 mai 1986 | 1123.62 lei 43-57 zile |
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Specificații
ISBN-13: 9780521038096
ISBN-10: 052103809X
Pagini: 512
Dimensiuni: 155 x 234 x 25 mm
Greutate: 0.71 kg
Editura: Cambridge University Press
Colecția Cambridge University Press
Seria Developmental and Cell Biology Series
Locul publicării:New York, United States
ISBN-10: 052103809X
Pagini: 512
Dimensiuni: 155 x 234 x 25 mm
Greutate: 0.71 kg
Editura: Cambridge University Press
Colecția Cambridge University Press
Seria Developmental and Cell Biology Series
Locul publicării:New York, United States
Cuprins
Preface; Glossary; Part I. Introduction: 1. The problem of aneuploidy; Part II. Clinical Observations: 2. The differentiability and variability of phenotypes; 3. The partitioning of phenotypes; Part III. The Theoretical Mechanisms and Issues: The Primary and Secondary Effects of Aneuploidy: 4. Gene dosage effects; 5. Metabolic pathways, transport systems and receptors; 6. Regulatory systems; 7. Assembly of macromolecules, cellular interactions and pattern formation; 8. Type and countertype; 9. Nonspecific effects of aneuploidy; Part IV. Experimental Systems for the Study of Mammalian and Human Aneuploidy: 10. Generation and properties of mouse aneuploids; 11. Models for human aneuploidy; Part V. Three Major Clinical Problems of Human Aneuploidy: 12. Trisomy 21 (Down syndrome); 13. Monosomy X (Turner syndrome, gonadal dysgenesis); 14. Cancer; Part VI. Conclusion: 15. Principles, mechanisms and models; Appendix; References; Index.
Descriere
This book considers chromosome imbalance which affects all stages of life in ways ranging from spontaneous abortion and retardation to behavioural problems and malignancy.