The Genetics and Development of Scoliosis
Editat de Kenro Kusumi, Sally L. Dunwoodieen Limba Engleză Paperback – 15 ian 2019
Our understanding of the genetic and developmental mechanisms underlying scoliosis is rapidly evolving, this timely second edition of The Genetics and Development of Scoliosis is to provide researchers, clinicians, and students with the most current views in this field.
This volume brings together leaders in understanding congenital and idiopathic scoliosis to present the current state of research, and to compare the genetic etiology of these conditions, in order to identify potential shared developmental mechanisms. This book will summarize the recent advances in studies of spinal development and how disruptions during embryogenesis in embryonic segmentation can lead to congenital vertebral defects. In addition, recent reports of genetic loci predisposing patients to develop juvenile and adolescent idiopathic scoliosis will be presented, and key clinical features are reviewed. Finally, there will be discussion of how genetic heterogeneity and gene-environment interactions may contribute to congenital scoliosis and isolated vertebral malformations.
This volume brings together leaders in understanding congenital and idiopathic scoliosis to present the current state of research, and to compare the genetic etiology of these conditions, in order to identify potential shared developmental mechanisms. This book will summarize the recent advances in studies of spinal development and how disruptions during embryogenesis in embryonic segmentation can lead to congenital vertebral defects. In addition, recent reports of genetic loci predisposing patients to develop juvenile and adolescent idiopathic scoliosis will be presented, and key clinical features are reviewed. Finally, there will be discussion of how genetic heterogeneity and gene-environment interactions may contribute to congenital scoliosis and isolated vertebral malformations.
| Toate formatele și edițiile | Preț | Express |
|---|---|---|
| Paperback (2) | 711.15 lei 6-8 săpt. | |
| Springer International Publishing – 15 ian 2019 | 711.15 lei 6-8 săpt. | |
| Springer – 7 sep 2014 | 1280.04 lei 6-8 săpt. | |
| Hardback (1) | 718.10 lei 6-8 săpt. | |
| Springer International Publishing – 22 iun 2018 | 718.10 lei 6-8 săpt. |
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Specificații
ISBN-13: 9783030079444
ISBN-10: 3030079449
Ilustrații: XII, 199 p. 29 illus., 12 illus. in color.
Dimensiuni: 155 x 235 mm
Greutate: 0.3 kg
Ediția:Softcover reprint of the original 2nd ed. 2018
Editura: Springer International Publishing
Colecția Springer
Locul publicării:Cham, Switzerland
ISBN-10: 3030079449
Ilustrații: XII, 199 p. 29 illus., 12 illus. in color.
Dimensiuni: 155 x 235 mm
Greutate: 0.3 kg
Ediția:Softcover reprint of the original 2nd ed. 2018
Editura: Springer International Publishing
Colecția Springer
Locul publicării:Cham, Switzerland
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Cuprins
Chapter1: Developmental and Functional Anatomy of the Spine.- Chapter2: Environmental Factors and Axial Skeletal Dysmorphogenesis.- Chapter3: Congenital Scoliosis and Segmentation Defects of the Vertebrae in the Genetic Clinic.- Chapter4: The Genetics Contributing to Disorders involving Congenital Scoliosis.- Chapter5: Animal Models of Idiopathic Scoliosis.- Chapter6: Current Understanding of Genetic Factors in Idiopathic Scoliosis.- Chapter7: Genetics and Functional Pathology of Idiopathic Scoliosis.- Chapter8: Adolescence and Scoliosis: Deciphering the Complex Biology of Puberty and Scoliosis.
Notă biografică
Kenro Kusumi, Ph.D., is a Professor in the School of Life Sciences at Arizona State University.Dr. Kusumi’s current research focuses on genomic analysis of spinal development and regeneration, and their applications to developing novel therapies for scoliosis and other spinal disorders.
Sally L. Dunwoodie, Ph.D., is a Professor at the University of New South Wales and Laboratory Head in the Developmental Biology and Stem Cell Division at the Victor Chang Cardiac Research Institute in Sydney. Dr. Dunwoodie's research focuses on identifying genetic and environmental factors that disrupt embryogenesis and cause birth defects.
Sally L. Dunwoodie, Ph.D., is a Professor at the University of New South Wales and Laboratory Head in the Developmental Biology and Stem Cell Division at the Victor Chang Cardiac Research Institute in Sydney. Dr. Dunwoodie's research focuses on identifying genetic and environmental factors that disrupt embryogenesis and cause birth defects.
Textul de pe ultima copertă
Our understanding of the genetic and developmental mechanisms underlying scoliosis is rapidly evolving, this timely second edition of The Genetics and Development of Scoliosis is to provide researchers, clinicians, and students with the most current views in this field.
This volume brings together leaders in understanding congenital and idiopathic scoliosis to present the current state of research, and to compare the genetic etiology of these conditions, in order to identify potential shared developmental mechanisms. This book will summarize the recent advances in studies of spinal development and how disruptions during embryogenesis in embryonic segmentation can lead to congenital vertebral defects. In addition, recent reports of genetic loci predisposing patients to develop juvenile and adolescent idiopathic scoliosis will be presented, and key clinical features are reviewed. Finally, there will be discussion of how genetic heterogeneity and gene-environment interactions may contribute to congenital scoliosis and isolated vertebral malformations.
This volume brings together leaders in understanding congenital and idiopathic scoliosis to present the current state of research, and to compare the genetic etiology of these conditions, in order to identify potential shared developmental mechanisms. This book will summarize the recent advances in studies of spinal development and how disruptions during embryogenesis in embryonic segmentation can lead to congenital vertebral defects. In addition, recent reports of genetic loci predisposing patients to develop juvenile and adolescent idiopathic scoliosis will be presented, and key clinical features are reviewed. Finally, there will be discussion of how genetic heterogeneity and gene-environment interactions may contribute to congenital scoliosis and isolated vertebral malformations.
Caracteristici
Written by leaders in genetic and developmental research on scoliosis and developmental studies of the spine The only book currently on the market that incorporates knowledge in clinical, genetic, and developmental aspects of scoliosis Recent developments in key clinical and moltecular genetic studies of these disorders are also discussed