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The Mitochondrion in Aging and Disease de H.D. Osiewacz

The Mitochondrion in Aging and Disease: Progress in Molecular Biology and Translational Science, cartea 127

H.D. Osiewacz
en Limba Engleză Hardback – 4 sep 2014
Mitochondria, the "power plants" of eukaryotic cells, are best known for the generation of adenosine triphosphate (ATP), the universal cellular "energy currency" of the cell, and the synthesis of different essential components. Mitochondrial dysfunction is known to lead to various degenerative disorders, disease, and aging. The Mitochondrion in Aging and Disease works to unravel the processes leading to mitochondrial impairments and of pathways involved in mitochondrial quality control and their impact on health and aging will be addressed.

  • Reviews current topics of interest
  • Written by experts in the field
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Specificații

ISBN-13: 9780123946256
ISBN-10: 0123946255
Pagini: 290
Ilustrații: black & white illustrations, colour illustrations, black & white line drawings, colour line drawings, black & white tables, figures
Dimensiuni: 152 x 229 x 18 mm
Greutate: 0.61 kg
Editura: ELSEVIER SCIENCE
Seria Progress in Molecular Biology and Translational Science

Public țintă

Scientists interested in basic function of mitochondria and the role of these organelles in aging and disease.

Cuprins

  1. The Mitochondrial Free Radical Theory of Aging
    Gustavo Barja
  2. Mitochondrial DNA Mutations in Aging
    Konstantin Khrapko and Doug Turnbull
  3. Mathematical Models of Mitochondrial Aging and Dynamics
    Axel Kowald and Edda Klipp
  4. Mitochondrial Dynamics in Aging and Disease
    Jürgen Bereiter-Hahn
  5. The Retrograde Response – A Conserved Compensatory Reaction to Damage from Within and from Without
    S. Michal Jazwinski
  6. Mitochondrial Acetylation and Genetic Models of Parkinson’s Disease
    Georg Auburger, Suzana Gispert and Marina Jendrach
  7. Mitochondrial Dysfunction: Cause and Consequence of Alzheimer’s Disease
    Kristina Friedland-Leuner, Carola Stockburger, Isabel Denzer, Gunter P. Eckert and Walter E. Müller
  8. Mitochondria in Cancer: Why Mitochondria are a Good Target for Cancer Therapy
    Lan-Feng Dong and Jiri Neuzil
  9. Estrogen and Mitochondria Function in Cardiorenal Metabolic Syndrome
     Guanghong Jia, Annayya R. Aroor and  James R. Sowers
  10. Advances in Development of Rechargeable Mitochondrial Antioxidants
    Alexander N. Lukashev, Maxim V. Skulachev, Victoria Ostapenko, Alla Yu. Savchenko, V. V. Pavshintsev and Vladimir P. Skulachev