The Molecular Biology of Arrestins de Louis M. Luttrell

The Molecular Biology of Arrestins: Progress in Molecular Biology and Translational Science, cartea 118

en Limba Engleză Hardback – 30 iul 2013

This special volume of Progress in Molecular Biology and Translational Science focuses on the molecular biology of arrestins, with contributions from leaders in the field. Arrestins have emerged as central players in the regulation of many facets of G protein-coupled receptor signaling. This volume covers a variety of topics with reviews written by experts in the field.

Contributions from leading authorities
Informs and updates on all the latest developments in the field

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Specificații

ISBN-13: 9780123944405
ISBN-10: 0123944406
Pagini: 536
Dimensiuni: 152 x 229 x 32 mm
Ediția:New.
Editura: ELSEVIER SCIENCE
Seria Progress in Molecular Biology and Translational Science

Public țintă

Students, researchers, microbiologists, molecular biologists

Cuprins

Part I: Perspective - The Duality of Arrestin Function
1. Arrestins Come of Age: A Personal Historical Perspective
Part II: The Molecular Biology of Arrestins
2. True Arrestins and Arrestin-Fold Proteins: A Structure-Based Appraisal

3. Structural Determinants of Arrestin Functions

4. Arrestins: Role in the Desensitization, Sequestration and Vesicular Trafficking of G Protein-Coupled Receptors

5. Arrestins as Regulators of Kinases and Phosphatases

6. ß-Arrestins: Modulators of Small GTPase Activation and Function

7. Arrestins and Protein Ubiquitination

8. Arrestins in Actin Reorganization and Cell Migration
Part III: The Physiological Roles of Arrestins
9. The Role of Arrestins in Development

10. The Role of Arrestins in Visual and Disease Processes of the Eye

11. b-Arrestins in the Central Nervous System

12. Arrestins in the Cardiovascular System

13. Arrestins in Bone

14. b-Arrestins in the Immune System

15. The Role of b-Arrestins in Cancer

16. Arrestins in Metabolic Regulation
Part IV: The Future - The Potential for Arrestin-based Therapeutics
17. Systems Analysis of Arrestin Pathway Functions

18. Arrestin Pathways as Drug Targets

Recenzii

Praise for the series: "Full of interest not only for the molecular biologist-for whom the numerous references will be invaluable-but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell." --British Medical Journal

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