Cantitate/Preț
Produs
Total produse
Vezi coșul
TOR: Target of Rapamycin de George Thomas

TOR: Target of Rapamycin: Current Topics in Microbiology and Immunology, cartea 279

Editat de George Thomas, David M. Sabatini, Michael N. Hall
en Limba Engleză Paperback – 21 oct 2012
 
TOR, the Target of Rapamycin was discovered a little over ten years ago in a genetic screen in S. cerevisiae in search of mutants resistant to the cytostatic effects of the antimycotic, rapamycin. Recent studies have placed TOR at the interface between nutrient sensing and the regulation of major anbolic and catabolic responses. The editors have gathered the leading figures in the field of TOR and its role in cellular homeostasis and human diseases.
Citește tot Restrânge

Toate formatele și edițiile

Toate formatele și edițiile Preț Express
Paperback (1) 136064 lei  6-8 săpt.
  Springer Berlin, Heidelberg – 21 oct 2012 136064 lei  6-8 săpt.
Hardback (1) 136467 lei  6-8 săpt.
  Springer Berlin, Heidelberg – 25 aug 2003 136467 lei  6-8 săpt.

Din seria Current Topics in Microbiology and Immunology

  • Hantaviruses
    Preț: 38779 lei
  • 18% Epstein Barr Virus Volume 1: One Herpes Virus: Many Diseases
    Preț: 92559 lei
  • 5% Epstein Barr Virus Volume 2: One Herpes Virus: Many Diseases
    Preț: 108058 lei
  • Marburg- and Ebolaviruses: From Ecosystems to Molecules
    Preț: 49976 lei
  • 5% Type IV Secretion in Gram-Negative and Gram-Positive Bacteria
    Preț: 31970 lei
  • 5% Coordinating Organismal Physiology Through the Unfolded Protein Response
    Preț: 31742 lei
  • 5% mRNA Vaccines
    Preț: 96779 lei
  • 18% Viral Fitness and Evolution: Population Dynamics and Adaptive Mechanisms
    Preț: 107622 lei
  • 5% T Cell Hybridomas: A Workshop at the Basel Institute for Immunology
    Preț: 68990 lei
  • 5% Tumorviruses, Neoplastic Transformation and Differentiation
    Preț: 68602 lei
  • 5% Current Topics in Microbiology and Immunology: Volume 102
    Preț: 68268 lei
  • 5% Retroviruses 1
    Preț: 68268 lei
  • 5% New Developments in Diagnostic Virology
    Preț: 69392 lei
  • 5% Mouse Mammary Tumor Virus
    Preț: 34626 lei
  • 5% Retroviruses 2
    Preț: 68498 lei
  • 5% Methylation of DNA
    Preț: 74551 lei
  • 15% The Molecular Biology of Adenoviruses I: 30 Years of Adenovirus Research 1953–1983
    Preț: 61586 lei
  • 5% The Molecular Biology of Adenoviruses 2: 30 Years of Adenovirus Research 1953–1983
    Preț: 68990 lei
  • 5% The Molecular Biology of Adenoviruses 3: 30 Years of Adenovirus Research 1953–1983
    Preț: 34682 lei
  • 5% Retroviruses 3
    Preț: 68094 lei
  • 5% Oncogenes in B-Cell Neoplasia: Workshop at the National Cancer Institute, National Institutes of Health, Bethesda, MD, USA, March 5–7, 1984
    Preț: 69043 lei
  • 5% Current Topics in Microbiology and Immunology
    Preț: 68920 lei
  • 5% Human T-Cell Leukemia Virus
    Preț: 69008 lei
  • 5% Iridoviridae
    Preț: 68442 lei
  • 5% The Biology of Trypanosomes
    Preț: 68498 lei
  • 5% Genetic Approaches to Microbial Pathogenicity
    Preț: 69113 lei
  • 5% Images of Biologically Active Structures in the Immune System: Their Use in Biology and Medicine
    Preț: 68268 lei
  • 5% Parasite Antigens in Protection, Diagnosis and Escape
    Preț: 35597 lei
  • 5% Bacteria and Complement
    Preț: 68532 lei
  • 5% The BALB/c Mouse: Genetics and Immunology
    Preț: 68937 lei
  • 5% Retroviruses 4
    Preț: 67989 lei
  • 5% Genetic Control of the Susceptibility to Bacterial Infection
    Preț: 68462 lei
  • 5% Protein Secretion and Export in Bacteria
    Preț: 68657 lei
  • 5% Specificity and Function of Clonally Developing T Cells
    Preț: 69322 lei
  • 5% The Wild Mouse in Immunology
    Preț: 69800 lei
  • 5% Current Topics in Microbiology and Immunology 128
    Preț: 68128 lei
  • 5% Current Topics in Microbiology and Immunology
    Preț: 68672 lei
  • 5% Peptides as Immunogens
    Preț: 67917 lei
  • 5% The Molecular Biology of Baculoviruses
    Preț: 68408 lei
  • 5% Mechanisms in B-Cell Neoplasia: Workshop at the National Cancer Institute, National Institutes of Health, Bethesda, MD,USA,March 24–26,1986
    Preț: 69656 lei
  • 5% Arenaviruses: Genes, Proteins, and Expression
    Preț: 68094 lei
  • 5% Arenaviruses: Biology and Immunotherapy
    Preț: 68832 lei
  • 5% Differentiation of B Lymphocytes
    Preț: 68303 lei
  • 5% The Molecular Biology of Bacterial Virus Systems
    Preț: 34557 lei
  • 5% Genetics of Immunological Diseases
    Preț: 36015 lei
  • 15% Carbohydrate-Protein Interaction
    Preț: 61131 lei
  • 5% Cytotoxic Effector Mechanisms
    Preț: 68109 lei
  • 5% Mechanisms in B-Cell Neoplasia 1988: Workshop at the National Cancer Institute, National Institutes of Health, Bethesda, MD, USA, March 23–25, 1988
    Preț: 69467 lei
  • 15% Human Retrovirology: Facts and Concepts
    Preț: 60895 lei

Preț: 136064 lei

Preț vechi: 143225 lei
-5% Nou

Puncte Express: 2041
Preț estimativ în valută:
26040€ • 27642$ • 21698£

Carte tipărită la comandă

Livrare economică 27 decembrie 24 - 10 ianuarie 25

 Adaugă în coș

Wish list
Gift list
Am citit!
Adaugă în listă
Preluare comenzi: 021 569.72.76

Specificații

ISBN-13: 9783642623608
ISBN-10: 3642623603
Pagini: 380
Ilustrații: X, 364 p.
Dimensiuni: 155 x 235 x 20 mm
Greutate: 0.53 kg
Ediția:Softcover reprint of the original 1st ed. 2004
Editura: Springer Berlin, Heidelberg
Colecția Springer
Seria Current Topics in Microbiology and Immunology

Locul publicării:Berlin, Heidelberg, Germany

Public țintă

Research

Cuprins

TOR: The First Ten Years.- The Role of Phosphatases in TOR Signaling in Yeast.- Yeast TOR Signaling: A Mechanism for Metabolic Regulation.- Nutrient Signaling Through TOR Kinases Controls Gene Expression and Cellular Differentiation in Fungi.- Autophagy in Yeast: A TOR-Mediated Response to Nutrient Starvation.- The Fission Yeast TOR Proteins and the Rapamycin Response: an Unexpected Tale.- Plant Growth and the TOR Pathway.- TOR Action in Mammalian Cells and in Caenorhabditis elegans.- Genetic Analysis of TOR Signaling in Drosophila.- Interplay Between Growth Factor and Nutrient Signaling: Lessons from Drosophila TOR.- mTOR Signaling to Translation.- Modulation of the Protein Kinase Activity of mTOR.- Role of mTOR Signaling in the Control of Translation Initiation and Elongation by Nutrients.- Novel Regulatory Mechanisms of mTOR Signaling.- Raptor and mTOR: Subunits of a Nutrient-Sensitive Complex.- Kinase Activities Associated with mTOR.- mTOR: A Mediator of Intracellular Homeostasis.- mTOR as a Positive Regulator of Tumor Cell Responses to Hypoxia.- Retroviral Oncogenes and TOR.- mTOR as a Target for Cancer Therapy.

Textul de pe ultima copertă

 
TOR, the Target of Rapamycin was discovered a little over ten years ago in a genetic screen in S. cerevisiae in search of mutants resistant to the cytostatic effects of the anti-mycotic, rapamycin. Since that time orthologues have been identified in all eukaryotes examined to date, including humans. Recent studies have placed TOR at the interface between nutrient sensing and the regulation of major anabolic and catabolic responses. The significance of understanding the molecular mechanisms which control TOR function has been underscored by Phase 1 clinical trials, showing that rapamycin is not only therapeutically important as an immunosuppressive but is also efficacious in the treatment of solid tumors. Indeed, currently, homologues of rapamycin are in broad-based trials to determine its use in the treatment of other pathological conditions, such as inflammation and restenosis. Given these observations a great deal of attention has been drawn to TOR and its role cellular homoeostasis and human disease. Here we have gathered the leading figures in the field to summarize their own contributions to uncovering TOR function and to speculate where they think the field will be moving in the next few years.