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Toxicity and Autophagy in Neurodegenerative Disorders de José M. Fuentes

Toxicity and Autophagy in Neurodegenerative Disorders: Current Topics in Neurotoxicity, cartea 9

Editat de José M. Fuentes
en Limba Engleză Hardback – 19 mai 2015
Comprehensive overview of different aspects of autophagy as it relates to neurodegenerative diseases. The pathogenesis of the main neurodegenerative disorders includes either the accumulation of altered or misfolded proteins or exposure to several toxics. Autophagy constitute one of the two principal cellular pathways implicate in the clearance of these material and can serve as a neuroprotective mechanism. Topics include: the role of autophagy in the brain, the role of autophagy in the principal neurodegenerative disorders, and the mechanism by which different molecules cause neurotoxicity and the role autophagy plays.
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Specificații

ISBN-13: 9783319139388
ISBN-10: 331913938X
Pagini: 360
Ilustrații: XV, 268 p. 34 illus., 27 illus. in color.
Dimensiuni: 155 x 235 x 22 mm
Greutate: 0.58 kg
Ediția:2015
Editura: Springer International Publishing
Colecția Springer
Seria Current Topics in Neurotoxicity

Locul publicării:Cham, Switzerland

Public țintă

Research

Cuprins

​Regulation of Autophagy In Health And Disease.- Role of Chaperone-Mediated Autophagy in Ageing and Neurodegeneration.- Interaction Between Mitochondria And Autophagy.- Dual role of autophagy in neurodegenerative diseases: The case of amyotrophic lateral sclerosis.- Autophagy pathways in Huntington’s disease.- Control of Autophagy in Parkinson’s Disease.- Autophagy in Alzheimer’s disease: a cleaning service out-of-order?.- Autophagy as a neuroprotective mechanism against 3-nitropropionic acid-induced cell death.- Paraquat: Molecular Mechanisms of Neurotoxicity and its Relation with Autophagy.- Agrochemicals-induced Dopaminergic Neurotoxicity:  Role of Mitochondria-mediated oxidative stress and Protein Clearance Mechanisms.- Molecular And Neurochemical Mechanisms Dopamine Oxidation To O-Quinones In Parkinson´S Disease Pathogenesis.- Exploring the Role of Autophagy in the Pathogenesis of Rotenone-Induced Toxicity.-  Autophagic pathology and calcium deregulation in neurodegeneration. .

Recenzii

“This is a very good book for students andresearchers involved with biochemical and cellular pathways of immune responsesafter cell toxicity due to neurodegenerative processes. I highly recommend thebook to neurologists, physiologists, and biochemists.” (Joseph J.  Grenier, Amazon.com, January, 2016)

Textul de pe ultima copertă

Comprehensive overview of different aspects of autophagy as it relates to neurodegenerative diseases. The pathogenesis of the main neurodegenerative disorders includes either the accumulation of altered or misfolded proteins or exposure to several toxics. Autophagy constitute one of the two principal cellular pathways implicate in the clearance of these material and can serve as a neuroprotective mechanism. Topics include: the role of autophagy in the brain, the role of autophagy in the principal neurodegenerative disorders, and the mechanism by which different molecules cause neurotoxicity and the role autophagy plays.

Caracteristici

Evaluates the interplay between autophagy and toxicity in neurodegenerative disease Contains contributions from an international group of experts Addresses the major diseases: Alzheimer's, Parkinson's, Huntington's Includes supplementary material: sn.pub/extras