Type IV Secretion in Gram-Negative and Gram-Positive Bacteria: Current Topics in Microbiology and Immunology, cartea 413
Editat de Steffen Backert, Elisabeth Grohmannen Limba Engleză Hardback – 23 mar 2018
Type IV secretion systems (T4SSs) are highly versatile membrane-associated transporter machines used by Gram-negative and Gram-positive bacteria to deliver substrate molecules to a large variety of target cells. This volume summarizes our current knowledge of the large variety and structural diversity of T4SSs in pathogenic Escherichia, Agrobacterium, Legionella, Coxiella, Bartonella, Helicobacter, Enterococcus and other species. Divided into 13 chapters contributed by leading experts, it presents findings that significantly enhance our understanding of how various pathogens manipulate host cell functions to trigger bacterial uptake, promote intracellular growth, suppress defense mechanisms and of how bacteria spread antibiotic resistances, thus facilitating bacterial colonization and disease development. The book is an invaluable source of information for researchers and clinicians.
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Specificații
ISBN-13: 9783319752402
ISBN-10: 3319752405
Pagini: 200
Ilustrații: XXII, 345 p. 43 illus. in color.
Dimensiuni: 155 x 235 x 28 mm
Greutate: 0.69 kg
Ediția:1st ed. 2017
Editura: Springer International Publishing
Colecția Springer
Seria Current Topics in Microbiology and Immunology
Locul publicării:Cham, Switzerland
ISBN-10: 3319752405
Pagini: 200
Ilustrații: XXII, 345 p. 43 illus. in color.
Dimensiuni: 155 x 235 x 28 mm
Greutate: 0.69 kg
Ediția:1st ed. 2017
Editura: Springer International Publishing
Colecția Springer
Seria Current Topics in Microbiology and Immunology
Locul publicării:Cham, Switzerland
Cuprins
Biological diversity of prokaryotic type IV secretion systems.- Evolution of type IV secretion systems and their substrates.- Structural and molecular biology of type IV secretion systems.- Relaxosome formation and transfer of broad-host range plasmids Gram-negative bacteria.- Mechanisms of conjugative transfer by Gram-positive broad-host range plasmids.- Social behavior and decision making in bacterial conjugation.- Structure and chemical biology approaches to understand type IV secretion system function and inhibition.- Type IV secretion systems: A pivotal tool to establish intracellular lifestyle by pathogens.- Subversion of host target cells by the Legionella type IV secretion system.- Role of multiple type IV secretion systems in Bartonella infections.- Requirements for T4SS effector protein translocation and function by the Coxiella Dot/Icm system.- Composition and function of the Helicobacter pylori cag type IV secretion system.- Secretion of chromosomal DNA by the gonococcal type IV secretion system.
Notă biografică
Prof. Dr. rer. nat. Steffen Backert
Chair of Microbiology
Friedrich Alexander University Erlangen/Nuremberg
Department of Biology
Division of Microbiology
Staudtstr. 5
D-91058 Erlangen
Germany
Tel. ++49 9131 8528081
Fax ++49 9131 8528082
Prof. Dr. techn. Elisabeth Grohmann
Professor of Microbiology
Beuth University of Applied Sciences Berlin
Department of Life Sciences and Technology
Division of Microbiology
Forum Seestraße
Seestr. 64
D-13347 Berlin
Germany
Tel. ++49 30 45043942
Fax ++49 30 45043983
Chair of Microbiology
Friedrich Alexander University Erlangen/Nuremberg
Department of Biology
Division of Microbiology
Staudtstr. 5
D-91058 Erlangen
Germany
Tel. ++49 9131 8528081
Fax ++49 9131 8528082
Prof. Dr. techn. Elisabeth Grohmann
Professor of Microbiology
Beuth University of Applied Sciences Berlin
Department of Life Sciences and Technology
Division of Microbiology
Forum Seestraße
Seestr. 64
D-13347 Berlin
Germany
Tel. ++49 30 45043942
Fax ++49 30 45043983
Textul de pe ultima copertă
Type IV secretion systems (T4SSs) are highly versatile membrane-associated transporter machines used by Gram-negative and Gram-positive bacteria to deliver substrate molecules to a large variety of target cells. This volume summarizes our current knowledge of the large variety and structural diversity of T4SSs in pathogenic Escherichia, Agrobacterium, Legionella, Coxiella, Bartonella, Helicobacter, Enterococcus and other species. Divided into 13 chapters contributed by leading experts, it presents findings that significantly enhance our understanding of how various pathogens manipulate host cell functions to trigger bacterial uptake, promote intracellular growth, suppress defense mechanisms and of how bacteria spread antibiotic resistances, thus facilitating bacterial colonization and disease development. The book is an invaluable source of information for researchers and clinicians.
Caracteristici
Offers new insights into the variety and structural diversity of type IV secretion systems Provides information on bacterial colonization and disease development Sheds new light on the manipulation of host cell functions by various pathogens