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Understanding Clinical Data Analysis: Learning Statistical Principles from Published Clinical Research

Autor Ton J. Cleophas, Aeilko H. Zwinderman
en Limba Engleză Paperback – 14 iun 2018
This textbook consists of ten chapters, and is a must-read to all medical and health professionals, who already have basic knowledge of how to analyze their clinical data, but still, wonder, after having done so, why procedures were performed the way they were. The book is also a must-read to those who tend to submerge in the flood of novel statistical methodologies, as communicated in current clinical reports, and scientific meetings.
In the past few years, the HOW-SO of current statistical tests has been made much more simple than it was in the past, thanks to the abundance of statistical software programs of an excellent quality. However, the WHY-SO may have been somewhat under-emphasized. For example, why do statistical tests constantly use unfamiliar terms, like probability distributions, hypothesis testing, randomness, normality, scientific rigor, and why are Gaussian curves so hard, and do they make non-mathematicians getting lost all the time? Thebook will cover the WHY-SOs.
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Specificații

ISBN-13: 9783319819174
ISBN-10: 3319819178
Pagini: 234
Ilustrații: X, 234 p. 211 illus., 92 illus. in color.
Dimensiuni: 155 x 235 mm
Greutate: 0.35 kg
Ediția:Softcover reprint of the original 1st ed. 2017
Editura: Springer International Publishing
Colecția Springer
Locul publicării:Cham, Switzerland

Cuprins

Preface.- Randomness.- Randomized and Observational Research.- Randomized Clinical Trials, Designs.- Randomized Clinical Trials, Analysis Sets, Statistical Analysis, Reporting Issues.- Discrete Data Analysis, Failure Time Data Analysis.- Quantitative Data Analysis.- Subgroup Analysis.- Interim Analysis.- Multiplicity Analysis.- Medical Statistics, a Discipline at the Interface of Biology and Mathematics.-Index.

Notă biografică

The authors are well-qualified in their field. Professor Zwinderman is past-president of the International Society of Biostatistics (2012-2015), and Professor Cleophas is past-president of the American College of Angiology (2000-2002). From their expertise they should be able to choose the best-help-there-is for making difficult issues understandable, that is real data examples from the global literature rather than hypothetical examples.
The authors have been working and publishing together for 18 years, and their research can be characterized as a continued effort to demonstrate that clinical data analysis is not mathematics but rather a discipline at the interface of philosophy, biology, and mathematics.
The authors, as professors and teachers in statistics at universities in The Netherlands and France for the most part of their lives, are convinced, that the scientific method of statistical reasoning and hypothesis testing is little used by physicians and otherhealth workers, and they hope, that the current production will help them find the appropriate ways for answering their scientific questions.   
Four textbooks complementary to the current production and written by the same authors are Statistics applied to clinical studies 5th edition, 2012, Machine learning in medicine a complete overview, 2015, SPSS for starters and 2nd levelers 2nd edition, 2015, Clinical Data Analysis on a Pocket Calculator 2nd edition, 2016, all of them edited by Springer Heidelberg Germany. 

 

Caracteristici

The book uses the best-help-there-is for making the difficult issues understandable by using real data examples rather than hypothetical examples Complementarily to real data examples, the book continually gives a philosophical treatise of the basics of the scientific method. The book explains all of the novel issues of clinical data analysis from the past few years.

Descriere

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This textbook consists of ten chapters, and is a must-read to all medical and health professionals, who already have basic knowledge of how to analyze their clinical data, but still, wonder, after having done so, why procedures were performed the way they were. The book is also a must-read to those who tend to submerge in the flood of novel statistical methodologies, as communicated in current clinical reports, and scientific meetings.
In the past few years, the HOW-SO of current statistical tests has been made much more simple than it was in the past, thanks to the abundance of statistical software programs of an excellent quality. However, the WHY-SO may have been somewhat under-emphasized. For example, why do statistical tests constantly use unfamiliar terms, like probability distributions, hypothesis testing, randomness, normality, scientific rigor, and why are Gaussian curves so hard, and do they make non-mathematicians getting lost all the time? The book will cover the WHY-SOs.