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Vascular Adhesion Molecules and Inflammation: Progress in Inflammation Research

Editat de Jeremy D. Pearson
en Limba Engleză Hardback – 31 aug 1999
Vascular adhesion molecules are vital for the physiological processes of leukocyte trafficking and also critically involved in the enhanced leukocyte emigration that is a key feature of all inflammatory and imm une diseases. The book will provide an overview of the roles of vascul ar adhesion molecules in health and disease, with chapters on their ce ll biology, followed by chapters reviewing their importance in specifi c disease processes. The book is designed to provide up-to-date, linke d reviews of the subject suitable for postgraduate students entering t he field or research workers from allied disciplines needing a modern overview.
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Specificații

ISBN-13: 9783764358006
ISBN-10: 3764358009
Pagini: 260
Greutate: 0.64 kg
Editura: Birkhauser Basel
Colecția Birkhauser
Seria Progress in Inflammation Research

Locul publicării:Basel, Switzerland

Public țintă

Research

Cuprins

How early studies of inflammation led to our current views on the roles of vascular adhesion molecules.- Adhesion of leukocytes from flow: The selectins and their ligands.- Co-operative signaling between leukocytes and endothelium mediating firm attachment.- Production and presentation of chemokines by endothelial cells.- Platelet-activating factor: A signaling molecule for leukocyte adhesion.- Tight junctions and adherens junctions in endothelial cells: Structure and regulation.- The role of PECAM in leukocyte emigration.- Selective lymphocyte migration into secondary lymphoid rrgans and inflamed tissues.- Oxidation-reduction sensitive regulation of vascular inflammatory gene expression.- Quantification and imaging of vascular adhesion molecule expression in inflammatory diseases in vivo.- Leukocyte adhesion and activation in xenografts.- Control of leukocyte adhesion and activation in ischemia-reperfusion injury.- Control of leukocyte adhesion and activation in atherogenesis.