This book constitutes the refereed post-conference proceedings of the 6^th International Conference on Mobile Communication and Healthcare, MobiHealth 2016, held in Milan, Italy, in November 2016. The 50 revised full papers were reviewed and selected from numerous submissions and are organized in topical sections covering: Technological development for m-health application user engagement.- IoT - Internet of Things.- Advances in soft wearable technology for mobile-health.- Emerging experiences into receiving and delivering healthcare through mobile and embedded solutions.- Advances in personalized healthcare services.- Mobile monitoring, and social media pervasive technologies.