This continuing series gathers and presents original research results on the leading edge of medicine and biology. Each article has been carefully selected in an attempt to present substantial topical data across a broad spectrum. Topics discussed in this compilation include the effects of hypertension in patients with epistaxis; chronic supportive otitis media in children; the effect of menopausal hormone therapy on breast atrophy; therapeutic targets for Huntington's Disease; catheter-related infections and mortality from congenital malformations in new-borns and infants.