In this issue of Veterinary Clinics: Small Animal Practice, guest editor Dr. Carlo Siracusa brings his considerable expertise to the topic of Canine and Feline Behavior. Top experts focus on the intersection between behavioral and physical health, keeping general veterinary practitioners and their needs in mind. The articles provide general practitioners with tools to detect behavior changes associated with physical disease, and to diagnose or rule out physical disease contributing to behavior problems before referring to a veterinary behavior specialist.