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Constitutive Activity in Receptors and Other Proteins, Part A de Melvin I. Simon

Constitutive Activity in Receptors and Other Proteins, Part A: Methods in Enzymology, cartea 484

Melvin I. Simon
en Limba Engleză Hardback – 25 noi 2010
This volume of Methods in Enzymology covers the current methodology for the detection and assessment of constitutively active proteins. The chapters written by expert authors who are leaders in the field, provide hints and tricks not available in primary research publications.It is extensively referenced, with useful figures and tables throughout the volume.


  • Expert authors who are leaders in the field
  • Extensively referenced and useful figures and tables
  • Provides hints and tricks to facilitate reproduction of methods
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Specificații

ISBN-13: 9780123812988
ISBN-10: 0123812984
Pagini: 804
Dimensiuni: 152 x 229 x 38 mm
Greutate: 1.25 kg
Editura: ELSEVIER SCIENCE
Seria Methods in Enzymology

Public țintă

Researchers and students in cell, molecular and developmental biology

Cuprins

Section I-- Identification and Measurement of Constitutive Activity
  1. Constitutive activity at the cannabinoid CB1 receptor and behavioral responses Katherine E. Hanlon and Todd W. Vanderah
  2. Detecting constitutive activity and protean agonism at the cannabinoid-2 receptor. Massimiliano Beltramo, Rossella Brusa, Isabella Mancini, Paola Scandroglio, Massimiliano. Beltramo
  3. Modulation of constitutive activity of the ghrelin receptor by use of pharmacological tools as well as mutagenesis Birgitte Holst and Jacek Mokrosinski
  4. Assessment of constitutive activity and internalization of GPR54 (Kiss1-r). Macarena Pampillo and Andy Videsh Babwah
  5. Assessment of Constitutive Activity in EP Prostanoid Receptors Hiromichi Fujino, Toshihiko Murayama, and John W. Regan
  6. a1D-Adrenergic receptors: constitutive activity and reduced expression at the plasma membrane J Adolfo Garcia-Sáinz, M. Teresa Romero-Ávila and Luz del Carmen Medina
  7. Constitutive activity of the histamine H1 receptor Saskia Nijmeijer, Rob Leurs and Henry F Vischer
  8. Constitutive activity of somatostatin receptor subtypes Anat Ben-Shlomo, Kolja Wawrowsky and Shlomo Melmed
  9. Assessment of homologous internalization of constitutively active N111G mutant of AT1 receptor Mohiuddin Ahmed Bhuiyan and Takafumi Nagatomo
  10. Methods to detect cell surface expression and constitutive activity of GPR6 Balakrishna M. Prasad, Bettye Hollins and Nevin A. Lambert
  11. ß3-adrenoceptor agonists and (antagonists as) inverse agonists: history, perspective, constitutive activity and stereospecific binding. Maria Grazia Perrone and Antonio Scilimati
  12. Constitutive Activity of the Lutropin Receptor and its Allosteric Modulation by Receptor Heterodimerization Deborah L. Segaloff
  13. Assessing Constitutive Activity of Extracellular Calcium-Sensing Receptors in Vitro and in Bone Wenhan Chang, Melita Dvorak, and Dolores Shoback
  14. Constitutive Activity of Neural Melanocortin Receptors. Ya-Xiong Tao, Hui Huang, Zhi-Qiang Wang, Fan Yang, Jessica N. Williams, and Gregory V. Nikiforovich
  15. Measurement of Constitutive Activity of BMP Type I receptors Peter ten Dijke
  16. Probing the CA among dopamine D1 and D5 receptors and their mutants Bianca Plouffe, Jean-Philippe D’Aoust, Vincent Laquerre, Binhui Liang and Mario Tiberi
  17. Identification of Gain-of-Function Variants of the Human Prolactin Receptor Vincent Goffin, Roman L. Bogorad, and Philippe Touraine
  18. Investigations of Activated ACVR1/ALK2, a Bone Morphogenetic Protein (BMP) Type I Receptor that Causes Fibrodysplasia Ossificans Progressiva Frederick. Kaplan, Petra Seemann, Julia Haupt, Meiqi Xu, Vitali Lounev, Mary Mullins, Eileen M. Shore
  19. Identification and evaluation of constitutively active thyroid stimulating hormone receptor mutations Joaquin Lado-Abeal, Leah R. Quisenberry, and Isabel Castro-Piedras
  20. Assessment of constitutive activity of a G protein-coupled receptor, Cpr2, in Cryptococcus neoformans by heterologous and homologous methods Chaoyang Xue, Yina Wang, and Yen-Ping Hsueh
  21. In vitro and in vivo assessment of mu opioid receptor constitutive activity. Edward J. Bilsky, Denise Giuvelis, Melissa D. Osborn, Christina M. Dersch, Heng Xu and Richard B. Rothman
  22. Constitutively active µ-opioid methods Mark. Connor and John Traynor
  23. Protein Kinase Ck2 is a Constitutively-Active Enzyme That Promotes Cell Survival: Strategies To Identify Ck2 Substrates and Manipulate Its Activity In Mammalian Cells Jacob P. Turowec, James S. Duncan, Ashley C. French, Laszlo Gyenis, Nicole A. St. Denis, Greg J. Vilk, and David W. Litchfield
  24. Assessment of Ck2 Constitutive Activity In Cancer Cells Maria Ruzzene, Giovanni Di Maira, Kendra Tosoni, and Lorenzo A. Pinna
  25. Structural basis of the constitutive activity of protein kinase CK2 Birgitte B. Olsen, Barbara Guerra, Karsten Niefind and Olar-Georg Issinger font error
  26. Measuring the Constitutive Activation of c-Jun N-terminal Kinase Isoforms Ryan T. Nitta, Shawn S. Badal, and Albert J. Wong
  27. Measurement of constitutive MAPK and PI3K/AKT signaling activity in human cancer cell lines. Keiran S.M. Smalley
  28. Constitutive activity of GPR40/FFA1: Intrinsic or assay dependent? Leigh A Stoddart and Graeme Milligan
  29. Constitutive activity of TRP channels: methods for measuring the activity and its outcome Baruch Minke
  30. Measurement of Orexin (Hypocretin) and Substance P Effects On Constitutively Active Inward Rectifier K+ Channels in Brain Neurons Yasuko Nakajima and Shigehiro Nakajima
  31. Characterization of G protein receptor kinase 4 and measuring its constitutive activity in vivo Bradley T. Andresen
  32. Voltage-clamp based methods for the detection of constitutively active acetylcholine-gated IK,ACh channels in the diseased heart Niels Voigt, Samy Makary, Stanley Nattel, Dobromir Dobrev
  33. Assaying Wave and WASH complex constitutive activities towards the Arp2/3 complex.
Emmanuel DERIVERY and Alexis GAUTREAU