This book provides a comprehensive account of the physical basis and the clinical applications of microbubble-based contrast agents. The principles underlying the use of specialized contrast-specific imaging techniques and the examination methodology are clearly described. The different clinical applications of microbubble-based agents are extensively explained with the aid of numerous high-quality illustrations, many of which are in color. In addition, research and therapeutic perspectives are addressed. All of the chapters are written by recognized experts in the field, ensuring that this volume will be of great value to everyone who has an interest in microbubble-based contrast agents, from physicists and researchers to clinical radiologists.