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Drug Transporters: Recent Advances and Emerging Technologies de Glynis Nicholls

Drug Transporters: Recent Advances and Emerging Technologies: RSC Drug Discovery, cartea 55

Editat de Glynis Nicholls, Kuresh Youdim, David Fox
en Limba Engleză Hardback – 9 aug 2016
Understanding and quantifying the effects of drug transporters within the human body is essential for modulating drug safety and efficacy. This book comprehensively reviews current knowledge and techniques in the transporter sciences and their relations to drug metabolism and pharmacokinetics. It will serve as an essential handbook of information for postgraduate students, academics, industrial scientists and regulators who wish to understand the role of transporters in absorption, distribution, metabolism, and excretion processes.
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Specificații

ISBN-13: 9781782628668
ISBN-10: 1782628665
Pagini: 293
Dimensiuni: 242 x 164 x 20 mm
Greutate: 0.54 kg
Editura: Royal Society Of Chemistry
Seria RSC Drug Discovery

Textul de pe ultima copertă

Understanding and quantifying the effects of membrane transporters within the human body is essential for modulating drug safety and drug efficacy. The first volume comprehensively reviewed current knowledge and techniques in the transporter sciences and their relations to drug metabolism and pharmacokinetics. In this second volume on Drug Transporters, emphasis is placed on emerging sciences and technologies, highlighting potential areas for future advances within the drug transporter field.

The topics covered in both volumes ensure that all relevant aspects of transporters are described across the drug development process, from "in silico" models and preclinical tools through to the potential impact of transporters in the clinic. Contributions are included from expert leaders in the field, at-the-bench industrial scientists, renowned academics and international regulators. Case studies and emerging developments are highlighted, together with the merits and limitations of the available methods and tools, and extensive references to reviews on specific in-depth topics are also included for those wishing to pursue their knowledge further.

As such, this text serves as an essential handbook of information for postgraduate students, academics, industrial scientists and regulators who wish to understand the role of transporters in absorption, distribution, metabolism, and excretion processes. In addition, it is also a useful reference tool on the models and calculations necessary to predict their effect on human pharmacokinetics and pharmacodynamics.

Descriere

This book comprehensively reviews current knowledge and techniques in the transporter sciences and their relations to drug metabolism and pharmacokinetics.