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G Protein-Coupled Receptors in Health and Disease, Part B: Progress in Molecular Biology and Translational Science, cartea 89

Ya-Xiong Tao
en Limba Engleză Hardback – 24 feb 2010
G protein-coupled receptors (GPCRs) transduce signals from a diverse array of endogenous ligands, including ions, amino acids, nucleotides, lipids, peptides, and large glycoprotein hormones. They are also responsible for our sensing of exogenous stimuli, including photons and odorants. GPCRs regulate almost every aspect of our physiological functions. It is estimated that 40% to 50% of currently used therapeutic drugs target GPCRs directly or indirectly. Because the current drugs target only a small portion of the GPCRs, opportunities for targeting the remaining GPCRs is enormous. This volume reviews the latest developments in this rapidly advancing field.

  • This series provides a forum for discussion of new discoveries, approaches, and ideas
  • Contributions from leading scholars and industry experts
  • Reference guide for researchers involved in molecular biology and related fields
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Specificații

ISBN-13: 9780123747563
ISBN-10: 0123747562
Pagini: 192
Dimensiuni: 152 x 229 x 18 mm
Greutate: 0.43 kg
Editura: ELSEVIER SCIENCE
Seria Progress in Molecular Biology and Translational Science

Locul publicării:United Kingdom

Public țintă

Researchers, professors and graduate students in biochemistry, chemistry, molecular biology, biotechnology, and medicine

Cuprins

1. Diseased G protein-coupled receptors: An Introduction
Ya-Xiong Tao
2. GPR56 and its related diseases
Xianhua Piao and Ze Tian
3. GnRHR mutations and hypogonadotropic hypogonadism
Nicholas de Roux
4. LHR mutations and reproductive disorders
Deborah L. Segaloff
5. FSHR mutations and reproductive disorders
Ya-Xiong Tao and Deborah L. Segaloff
6. V2R mutations and nephrogenic diabetes insipidus
Daniel G. Bichet
7. Calcium-sensing receptor mutations
Geoffrey N. Hendy
8. Diseases caused by prostacyclin receptor mutations
John Hwa and Kathleen A Martin

Recenzii

PRAISE FOR THE SERIES
"Full of interest not only for the molecular biologist-for whom the numerous references will be invaluable-but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell."
--British Medical Journal