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Heart Failure: Handbook of Experimental Pharmacology, cartea 243

Editat de Johann Bauersachs, Javed Butler, Peter Sandner
en Limba Engleză Paperback – 12 mai 2018
This special issue of the Handbook of Experimental Pharmacology on Heart Failure covers the entire spectrum of the field, from the current understanding and definitions of heart failure, to epidemiology and the importance of co-morbidities, clinical trial design and biomarkers, as well as imaging technologies. The main focus of this book is to review current and emerging heart failure therapies and potential targets for treatment.
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Specificații

ISBN-13: 9783319866734
ISBN-10: 3319866737
Pagini: 581
Ilustrații: IX, 581 p. 100 illus., 30 illus. in color.
Dimensiuni: 155 x 235 mm
Greutate: 0.86 kg
Ediția:Softcover reprint of the original 1st ed. 2017
Editura: Springer International Publishing
Colecția Springer
Seria Handbook of Experimental Pharmacology

Locul publicării:Cham, Switzerland

Cuprins

Introduction.- Epidemiology.- Clinical trial design, endpoints and regulatory requirements. Biomarkers HFpEF/HFrEF. Imaging Technologies / MRI and Echo. Comorbidities in HF. Current Guideline based therapy of HFreF and HFpEF. New and Emerging Therapies and Targets. Ivabradine.- Beta3 agonists.- Novel MRAs.- pGCs and Natriuretic peptides.- sGC stimulators.- PDE’s.- Adenosin and A1 Agonists.- Myosin heavy chain / Troponin.- Stem cells.- Diuretics and Vasopressin.- GeneTherapy.- RNA-based therapies and micro RNAs.- Cardiac myosin activation using gene therapy.- Bendavia – mitochondrial therapies.- WNT signaling.- Anticoagulation therapy and NOACS in HF.- Potassium Binders.- Iron.           

Caracteristici

Comprehensive and state of the art overview of current and emerging heart failure treatments Up to date information on treatment guidelines and clinical trials in heart failure Authorships of worldwide heart failure experts from both academia and industry