This volume presents a study of the vernacular tradition of Chirurgia magna, one of the most important chirurgical treatises of the Middle Ages. Alongside an edition of the 15th-century Bergamo vernacular translation, based on ms. MA 501, it provides a historical-linguistic analysis and a glossary meant to illustrate the relationship between Latin and the vernacular in the formation of a medical terminology in the 14th and 15th centuries.