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Lipid Metabolism in Tumor Immunity: Advances in Experimental Medicine and Biology, cartea 1316

Editat de Yongsheng Li
en Limba Engleză Paperback – 20 mar 2022
This book focuses on lipid metabolism in tumor immunity, covering the application of lipidomics in tumor immunity and all aspects of lipid metabolism in tumor microenvironment. During the progression of tumors, tumor cells and immune cells interact in a dynamic microenvironment. Targeting the immune system has a high potential for treating cancer. However, due to the high heterogeneity of the tumor microenvironment, only a small percentage of patients experience such clinical benefits of tumor immunotherapy. Therefore, understanding the tumor microenvironment is crucial for tumor immunity. Recently, lipid metabolism is an emerging research direction and contributes to cell survival and biofunctions in tumor microenvironment, which is of great interest and significance to be elucidated. This book provides the doctors, researchers, and scientists with a cutting-edge overview of the lipid metabolism and its role in tumor immunity. It also yields benefits for pharmaceutical companies regarding drug discovery. 

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Specificații

ISBN-13: 9789813367876
ISBN-10: 9813367873
Ilustrații: XI, 211 p. 24 illus., 23 illus. in color.
Dimensiuni: 178 x 254 mm
Greutate: 0.4 kg
Ediția:1st ed. 2021
Editura: Springer Nature Singapore
Colecția Springer
Seria Advances in Experimental Medicine and Biology

Locul publicării:Singapore, Singapore

Cuprins

1. Introduction: Introduction of lipids, lipid metabolism and tumor immunity.- 2. ipid metabolism and lipidomics.- 3. Applications of lipidomics in tumour immunity.-4.  Overview: Lipid metabolism in tumour microenvironment.- 5. Lipid metabolism in cancer cells.- 6. Lipid metabolism in tumour-associated NK.- 7. Lipid metabolism in tumour-associated macrophages.- 8. Lipid metabolism in tumour-associated MDSCs.- 9. Lipid metabolism in tumour-associated fibroblasts.- 10. Lipid metabolism in tumour-associated B cells.- 11. Lipid metabolism in tumour-infiltrating T cells.- 12.   Lipid metabolism and angiogenesis.- 13. Lipid metabolism and tumor antigen-presenting.- 14. Lipid metabolism and immune checkpoints.

Notă biografică

Dr. Yongsheng Li now is Professor and Deputy Director of Clinical Medicine Research Center in Xinqiao Hospital, Army Medical University in Chongqing, China. He obtained his M.D. from Yunyang Medical College of Tongji Medical University in 2005 and his Ph.D. from Huazhong University of Science and Technology in 2009, respectively. After that, he was Research Fellow in Beth Israel Deaconess Medical Center. Later, from 2010 to 2015, he continued his post-doctoral training in Brigham and Women’s Hospital in the USA as research fellow. In 2016, he moved back to China and joined Army Medical University  (A.K.A. Third Military Medical University) and the same year, he was selected in the "Youth 1000 Talent Plan" of China.

Textul de pe ultima copertă

This book focuses on lipid metabolism in tumor immunity, covering the application of lipidomics in tumor immunity and all aspects of lipid metabolism in tumor microenvironment. During the progression of tumors, tumor cells and immune cells interact in a dynamic microenvironment. Targeting the immune system has a high potential for treating cancer. However, due to the high heterogeneity of the tumor microenvironment, only a small percentage of patients experience such clinical benefits of tumor immunotherapy. Therefore, understanding the tumor microenvironment is crucial for tumor immunity. Recently, lipid metabolism is an emerging research direction and contributes to cell survival and biofunctions in tumor microenvironment, which is of great interest and significance to be elucidated. This book provides the doctors, researchers, and scientists with a cutting-edge overview of the lipid metabolism and its role in tumor immunity. It also yields benefits for pharmaceutical companies regarding drug discovery. 


Caracteristici

Provides an overview of lipid metabolism in tumor immunity Promotes the understanding of lipidomics and its applications Sheds light on both basic and clinical research on tumor immunotherapy, as well as potential drug discovery