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Molecular Biology of Protein Folding, Part A: Progress in Molecular Biology and Translational Science, cartea 83

Editat de P. Michael Conn
en Limba Engleză Hardback – 18 dec 2008
The importance of protein folding has been recognized for many years. It is the underlying etiology in a large number of human diseases and it appears to be a novel method for cellular regulation of the expression of newly translated proteins. These volumes (Parts A & B) address this important topic. As a volume in Progress in Nucleic Acid Research and Molecular Biology, this book provides the latest information on the expanding research being conducted on protein folding.

  • Follow the new editor-in-chief, P. Michael Conn, as he introduces this first thematic volume in the series – an in-depth aid to researchers who are looking for the best techniques and tools for understanding the complexities of protein folding
  • Understand the advantages of protein folding over other therapeutic approaches and see how protein folding plays a critical role in the development of diseases such as Alzheimer’s and diabetes
  • Decipher the rules of protein folding through compelling and timely reviews combined with chapters written by international authors in engineering, biochemistry, physics and computer science
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Specificații

ISBN-13: 9780123745941
ISBN-10: 0123745942
Pagini: 288
Dimensiuni: 152 x 229 x 23 mm
Greutate: 0.52 kg
Editura: ELSEVIER SCIENCE
Seria Progress in Molecular Biology and Translational Science


Public țintă

Researchers in molecular biology, biochemistry, cell biology, and genetics

Cuprins

1. Stability and design of alpha-helical peptides - Andrew Doig

2. Under-wrapped protein folds in disease and epigenetic change - Ariel Fernandez

3. Self-organizing dynamics in protein folding - Bernard S. Gerstman

4. Diffusive models for protein folding - Stephen J Hagen

5. Toward reliable simulations of protein folding, misfolding and aggregation - Ulrich HE Hansmann

6. Single-molecule fluorescence studies of protein folding - Gilad Haran

7. Algorithms for protein folding - Sorin Istrail

8. Use of protein engineering techniques to elucidate protein folding pathways - Sophie Jackson

9. The kinetic stabilities of wild-type and disease-associated mutants of aromatic amino acid hydroxylases. Effect of natural chaperone ligand - Aurora Martinez

10. Chaperone-assisted protein folding in the endoplasmic reticulum - Maurizio Molinari

11. Protein folding over marginal barriers: ensembles, dynamics and stochastics - Victor Munoz