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New Concepts in Cerebral Ischemia: Frontiers in Neuroscience

Editat de Rick C. S. Lin
en Limba Engleză Hardback – 21 dec 2001
Approximately half a million Americans suffer brain ischemic episodes every year. These brain strokes are the third leading cause of death in the United States and the number-one cause of permanent disability. Over the past decade, we have made extensive attempts to understand the biological mechanisms that underlie stroke-induced neuronal injury. This research has been benefited by the introduction of a variety of new technologies and assays aimed at deciphering the complex neuronal degenerating processes triggered by cerebral vascular disorders or other neurological diseases that produce ischemic episodes.

New Concepts in Cerebral Ischemia presents techniques and theories for understanding the various stages of early pathogenesis in order to design specific strategies to protect neurons from further injury. Short, specific, and comprehensive chapters provide detailed descriptions of the new methods employed in both basic and clinical research that are revolutionizing the field of ischemia research. Written by international experts in CNS dysfunction, the book includes methods to elucidate the pathogenesis of ischemia, technologies used in the design of specific strategies to protect neurons from further injury, and new approaches to treat patients with acute ischemic episodes. With this book, you will gain new insights not only into cerebral vascular research, but also into neurological disease in general.
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Specificații

ISBN-13: 9780849301193
ISBN-10: 084930119X
Pagini: 330
Ilustrații: 38 b/w images
Dimensiuni: 156 x 234 x 23 mm
Greutate: 0.64 kg
Ediția:New.
Editura: CRC Press
Colecția CRC Press
Seria Frontiers in Neuroscience


Public țintă

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Cuprins

Gender Differences in Post-Ischemic and Post-Traumatic Brain Injury. Neonatal Hypoxic-Ischemic Insults and Its Mechanism. Neural Stem Cell Biology Provides Insights into New Therapeutic Strategies for Hypoxic-Ischemic Brain-Injury. Cellular and Molecular Mechanisms of Ischemic Tolerance. Excitotoxicity, Oxidative Stress, and Apoptosis in Ischemic Neuronal Death. Immediate and delayed Factors Causing Neuronal Death after Ischemic and Excitotoxic Insults. Mechanism of Zinc-Induced Neuronal Death. Cerebral Ischemia and Adenosine. Calpain and Caspase in Ischemic and Traumatic Brain Injury. The Potential Role of Hyperbaric Oxygen Therapy as an Adjunctive Treatment Modality for Stroke. Brain Inflammation, Cytokines, and p38AP Kinase Signaling in Stroke.

Descriere

Providing a detailed description of the techniques and theories employed in both basic and clinical research, New Concepts in Cerebral Ischemia delineates the mechanisms underlying neuronal damage induced by ischemia. The book covers methods to elucidate the pathogenesis of ischemia, technologies used in the design of specific strategies to protect neurons from further injury, and new approaches to treat patients with acute ischemic episodes. It includes methods and therapeutic approaches for neuronal protection against acute and chronic ischemic episodes and describes new animal models for ischemia research including the application of transgenic animals.