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Serotonin Receptors in Neurobiology: Frontiers in Neuroscience

Editat de Amitabha Chattopadhyay
en Limba Engleză Hardback – 17 mai 2007
A number of developments spanning a multitude of techniques makes this an exciting time for research in serotonin receptors. A comprehensive review of the subject from a multidisciplinary perspective, Serotonin Receptors in Neurobiology is among the first books to include information on serotonin receptor knockout studies. With contributions from leading experts in their fields, the book explores serotonin receptors from a broad-based, multidisciplinary approach. The approaches described vary from molecular biological techniques to fluorescence microscopy and imaging, to genetic manipulation in animal models, providing a wide range of tools to study serotonergic phenomena.

While each of these approaches has its own advantages and limitations, the synthesis of information and knowledge achieved from studies using multiple approaches will result in a comprehensive understanding of the underlying complex phenomena involved in serotonergic signaling and its implications in health and disease. The book provides an overall understanding of these receptors based on currently used methodologies and techniques. It describes specific experimental procedures that will be of use to researchers interested in addressing similar problems involving other G-protein-coupled receptor signaling systems.
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Specificații

ISBN-13: 9780849339776
ISBN-10: 0849339774
Pagini: 224
Ilustrații: 34 b/w images, 8 color images, 2 tables, 9 halftones and 22 equations
Dimensiuni: 156 x 234 x 18 mm
Greutate: 0.95 kg
Ediția:1
Editura: CRC Press
Colecția CRC Press
Seria Frontiers in Neuroscience


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Professional

Cuprins

Quantitative Imaging of Serotonin Autofluorescence with Multiphoton Microscopy. Monitoring Receptor-Mediated Changes of Intracellular cAMP Level by Using Ion Channels and Fluorescent Proteins as Biosensors. Membrane Organization and Dynamics of the Serotonin1A Receptor Monitored Using Fluorescence Microscopic Approaches. Calmodulin Is a 5-HT Receptor-Interacting and Regulatory Protein. Identification of Novel Transcriptional Regulators in the Nervous System, F. Remes-Lenicov. Serotonin 2A (5-HT2A) Receptor Function: Ligand-Dependent Mechanisms and Pathways. The 5-HT1A Receptor: A Signaling Hub Linked to Emotional Balance. Do Limits of Neuronal Plasticity Represent an Opportunity for Mental Diseases, Such as Addiction to Food and Illegal Drugs? Use and Utilities of Serotonin Receptor Knock-Out Mice. Use of Mice with Targeted Genetic Inactivation in the Serotonergic System for the Study of Anxiety. Index.

Descriere

Modulating mood, appetite, sexual activity, body temperature, and sleep, serotonin has implications in numerous disease states, including depression, anxiety, social phobia, schizophrenia, obsessive-compulsive disorder, and panic disorder. Providing the first comprehensive book on the subject from a multidisciplinary perspective, Serotonin Receptors in Neurobiology is among the first books to be published after serotonin receptor knock-out studies. With contributions from leading experts in their fields, this book covers a range of topics from contemporary techniques in receptor research to fundamental interactions of the 5-HT receptors with the lipid bilayer to behavioral studies.