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Oligomerization in Health and Disease de Jesus Giraldo

Oligomerization in Health and Disease

Jesus Giraldo, Francisco Ciruela
en Limba Engleză Hardback – 2 iul 2013
This special volume of Progress in Molecular Biology and Translational Science focuses on oligomerization in health and disease.

  • Contributions from leading authorities
  • Informs and updates on all the latest developments in the field
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Specificații

ISBN-13: 9780123869319
ISBN-10: 0123869315
Pagini: 656
Dimensiuni: 152 x 229 x 38 mm
Editura: Elsevier LTD, Oxford

Public țintă

Researchers, professors and graduate students in biochemistry, chemistry, molecular biology, biotechnology, and medicine.

Cuprins

Section I. Structural, Physico-Chemical, and Evolutionary Aspects of Protein Oligomerization
  1. Evolutionary, Physico-Chemical and Functional Mechanisms of Protein Homooligomerization
  2. Structural, Evolutionary and Assembly Principles of Protein Oligomerization
  3. Physico-Chemical Principles of Protein Aggregation
  4. Structural Aspects of Amyloid FormationSection II. Oligomerization in Seven-Transmembrane Receptors
  5. Quaternary Structure Predictions and Structural Communication Features of GPCR Dimers
  6. Challenges in the Development of Heteromer-GPCR-Based Drugs
  7. Oligomerization of GPCRs in Health and Disease on "Di/Oligomerisation of GPCRS; Mechanisms and Functional Significance"
  8. G Protein-Coupled Receptor Heterocomplexes in Neuropsychiatric Disorders
  9. Disease-Specific Heteromerization of G Protein-Coupled Receptors that Target Drugs of AbuseSection III. Oligomerization in Ion Channels
  10. Social Networking among Voltage-Gated Potassium Channels
  11. Oligomerization of the Mitochondrial Protein VDAC1: From Structure to Function and Cancer Therapy
  12. Consequences of Dimerization of the Voltage Gated Proton Channel
  13. Receptor Heteromeric Assembly, How it Works and Why it Matters - The Case of Ionotropic Glutamate ReceptorsSection IV. Oligomerization in Enzymes
  14. The Structural Basis for the Allosteric Regulation of Ribonucleotide Reductase
  15. Oligomerization of Dynamin Superfamily Proteins in Health and Disease
  16. Multimerization of the Dnmt3a DNA Methyltransferase and its Functional Implications
  17. Oligomerization in Endoplasmic Reticulum Stress SignalingSection V. Oligomerization in Regulatory Proteins
  18. Toll-IL-1-Receptor-Containing Adaptor Molecule-1 (TICAM-1), a Signaling Adaptor Linking Innate Immunity to Adaptive Immunity
  19. Assembly of Gamma-Tubulin Ring Complexes: Implications for Cell Biology and Disease
  20. Chemokine Oligomerization in Cell Signaling and Migration
  21. Oligomerization of Rab/Effector Complexes in the Regulation of Vesicle Trafficking

Recenzii

Praise for the series: "Full of interest not only for the molecular biologist-for whom the numerous references will be invaluable-but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell." --British Medical Journal