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Oligomerization in Health and Disease: From Enzymes to G Protein-Coupled Receptors de Jesus Giraldo

Oligomerization in Health and Disease: From Enzymes to G Protein-Coupled Receptors: Progress in Molecular Biology and Translational Science, cartea 169

Jesus Giraldo, Francisco Ciruela
en Limba Engleză Hardback – 28 ian 2020
Oligomerization in Health and Disease: From Enzymes to G Protein-Coupled Receptors, Volume 169 in the Progress in Molecular Biology and Translational Science series, provides in-depth reviews on topics of exceptional scienti?c importance. Topics of note in this new release include Computational prediction and re-design of aberrant oligomerization, Oligomerization of G protein-coupled receptors: an historical overview, Prediction and targeting of GPCR oligomer interfaces, GPCR Oligomerization dynamics: Functional consequences, GPCR heteromerization in neuropsychiatric disorders, Structural basis of regulation and oligomerization of human cystathionine ß-synthase, and Oligomerization of Porphobilinogen Synthase.


  • Includes comprehensive coverage of molecular biology
  • Presents ample use of tables, diagrams, schemata and color figures to enhance the reader's ability to rapidly grasp the information provided
  • Contains contributions from renowned experts in the field of molecular biology
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Specificații

ISBN-13: 9780128179291
ISBN-10: 0128179295
Pagini: 348
Dimensiuni: 152 x 229 mm
Greutate: 0.64 kg
Editura: ELSEVIER SCIENCE
Seria Progress in Molecular Biology and Translational Science

Public țintă

Each volume of Progress in Molecular Biology and Translational Science will be useful for scientists working actively in a field, including those at levels ranging from graduate student to senior investigator. Volumes also are appropriate for new investigators to a field who wish to familiarize themselves with the latest work.

Cuprins

1. Fluorescence microscopy methods for the study of protein oligomerization Roberto Arturo Petazzi, Amit Koikkarah Aji and Salvatore Chiantia 2. Computational prediction and redesign of aberrant protein oligomerization Jaime Santos, Valentín Iglesias and Salvador Ventura 3. Porphobilinogen synthase: An equilibrium of different assemblies in human health Eileen K. Jaffe 4. Prediction and targeting of GPCR oligomer interfaces Carlos A.V. Barreto, Salete J. Baptista, António José Preto, Pedro Matos-Filipe, Joana Mourão, Rita Melo and Irina Moreira 5. Integrated structural modeling and super-resolution imaging resolve GPCR oligomers Francesca Fanelli, Aylin C. Hanyaloglu and Kim Jonas 6. Exploring functional consequences of GPCR oligomerization requires a different lens Kyla Bourque, Jace Jones-Tabah, Dominic Devost, Paul B.S. Clarke and Terence E. Hébert 7. Continuing challenges in targeting oligomeric GPCR-based drugs Joaquin Botta, Julia Appelhans and Peter J. McCormick 8. Adenosine A2A-dopamine D2 receptor-receptor interaction in neurons and astrocytes: Evidence and perspectives Diego Guidolin, Manuela Marcoli, Cinzia Tortorella, Guido Maura and L. Francesco Agnati 9. Genetic variants in dopamine receptors influence on heterodimerization in the context of antipsychotic drug action Faron-Górecka Agata, Kusmider Maciej, Solich Joanna, Górecki Andrzej and Dziedzicka-Wasylewska Marta 10. Oligomerization of G protein-coupled receptors: Still doubted? Sergi Ferré, Francisco Ciruela, Vicent Casadó and Leonardo Pardo

Recenzii

"This is a very important book that covers protein oligomerization in health and disease and provides essential knowledge of the oligomeric protein biology, which is critical to allow pharmacologic interventions in diseases associated with oligomeric protein malfunction. This is a unique book dedicated to fully explaining all about protein oligomerization." --Doody