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Pediatric Demyelinating Diseases of the Central Nervous System and Their Mimics: A Case-Based Clinical Guide

Editat de Emmanuelle Waubant, Timothy E. Lotze
en Limba Engleză Hardback – 17 noi 2017
This collection of pediatric clinical cases focus on multiple sclerosis, neuromyelitis optica, acute disseminated encephalomyelitis and mimics.  Dedicated sections on diseases affecting the brain, brainstem, spinal cord and the optic nerve feature chapters that include the diagnostic work up, therapeutic management and case outcome.  Typical and atypical presentations of various pediatric demyelinating diseases also emphasize therapy response and those that breakthrough on treatment.  Filling a critical gap in the literature on inflammatory disorders of the central nervous system, all those that treat patients with these rare and challenging disorders will find this book extremely helpful for their daily clinical practice.
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Specificații

ISBN-13: 9783319614052
ISBN-10: 3319614053
Pagini: 347
Ilustrații: XV, 347 p. 166 illus., 24 illus. in color.
Dimensiuni: 155 x 235 mm
Greutate: 0.69 kg
Ediția:1st ed. 2017
Editura: Springer International Publishing
Colecția Springer
Locul publicării:Cham, Switzerland

Cuprins

SECTION I: Diseases that Affect the Brain.- 1. Acute Disseminated Encephalomyelitis.- 2. Acute Necrotizing Encephalopathy mimicking ADEM.- 3. Pediatric Multiple Sclerosis Manifesting with Primary Psychiatric Symptoms.- 4. Multiple Sclerosis in the Extremely Young.- 5. Breakthrough Disease in Pediatric MS.- 6. Neuromyelitis Optica Spectrum Disorder with Neuropsychiatric Presentation.- 7. Pediatric Tumefactive Demyelination.- 8. Radiologically Isolated Syndrome.- 9. Anti-Glutamic Acid Decarboxylase Limbic Encephalitis.- 10. Anti-NMDA Receptor Antibody Encephalitis.- 11. Pediatric Central Nervous System Vasculitis.- 12. Neuroinflammatory disease in association with Morphea (Localized Scleroderma).- 13. Susac’s Syndrome.- 14. Infectious Mimics of Multiple Sclerosis.- 15. Central nervous system lymphoma.- 16. Methotrexate Toxicity.- 17. Alexander Disease Type II.- 18. Neurodegenerative Langerhans Cell Histiocytosis.- 19. X-linked Adrenoleukodystrophy.- 20. Rapid-onset Obesity withHypothalamic dysfunction, Hypoventilation and Autonomic Dysregulation (ROHHAD).- 21. ADEM Mimic with Thiamine Transporter Deficiency.- SECTION II: Diseases that Affect the Brainstem.- 22. Acute Disseminated Encephalomyelitis-Brainstem and Cerebellar Presentation.- 23. Multiple Sclerosis with Brainstem Presentation.- 24. Neuromyelitis Optica Spectrum Disorder with Brainstem Presentation.- 25. Infection mimics with brainstem presentation.- 26. Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids.- SECTION III: Diseases that Affect the Spinal Cord.- 27. Acute Disseminated Encephalomyelitis with Spinal Cord Presentation.- 28. Post-Infectious Acute Transverse Myelitis.- 29. Complete transverse myelitis (idiopathic).- 30. Transverse Myelitis with Acute Inflammatory Polyradiculoneuropathy.- 31. Acute Flaccid Myelitis.- 32. Neuromyelitis optica spectrum disease with transverse myelitis presentation.- 33. Transverse myelitis in lupus.- 34.Acute Demyelination associated with TNF alpha- inhibiting biologic therapy.- 35. Myelopathy due to occult trauma mimicking transverse myelitis.- 36. Hypomyelination with Brainstem and Spinal Cord Abnormalities and Leg Spasticity (HBSL).- SECTION IV: Diseases That Affect the Optic Nerve.- 37. Acute disseminated encephalomyelitis followed by recurrent or monophasic optic neuritis.- 38. Chronic Relapsing Inflammatory Optic Neuropathy (CRION).- 39. Optic Neuritis as the Presenting Symptom for MS.- 40. Steroid Dependent Recurrent Optic Neuritis in Pediatric Multiple Sclerosis.- 41. Neuromyelitis optica presenting with bilateral optic neuritis.- 42. Sarcoidosis with Optic Nerve Presentation.



Notă biografică

Emmanuelle Waubant, MD, PhD
Professor of Neurology and Pediatrics
University of California San Francisco
San Francisco, CA, USA
 
Timothy E. Lotze, MD
Associate Professor of Child Neurology
Department of Pediatrics; Division of Neurology and Developmental Neuroscience
Baylor College of Medicine / Texas Children’s Hospital   
Houston, TX, USA



Textul de pe ultima copertă

This collection of pediatric clinical cases focus on multiple sclerosis, neuromyelitis optica, acute disseminated encephalomyelitis and mimics.  Dedicated sections on diseases affecting the brain, brainstem, spinal cord and the optic nerve feature chapters that include the diagnostic work up, therapeutic management and case outcome.  Typical and atypical presentations of various pediatric demyelinating diseases also emphasize therapy response and those that breakthrough on treatment.  Filling a critical gap in the literature on inflammatory disorders of the central nervous system, all those that treat patients with these rare and challenging disorders will find this book extremely helpful for their daily clinical practice.



Caracteristici

A valuable clinical case selection of various pediatric demyelinating diseases Cases include typical and atypical presentations and those that are responsive or breakthrough on treatment Helpful resource for neurologists, pediatricians and allied health professionals Includes supplementary material: sn.pub/extras