In this issue of Orthopedic Clinics, guest editors from the esteemed Campbell Clinic bring their considerable expertise to the topic of Perioperative Risks in Orthopedics. Articles cover key issues in pediatrics, shoulder and elbow, knee/hip, and hand and wrist surgery, with the goal of assisting healthcare providers in improving patient outcomes, reducing the incidence of complications, and enhancing the quality of life for patients undergoing orthopedic surgery.