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Phytochemical Investigations of Genus Terminalia: Phytochemical Investigations of Medicinal Plants

Autor Brijesh Kumar, Awantika Singh, K. P. Madhusudanan
en Limba Engleză Paperback – 9 oct 2024
Genus Terminalia is known to be a rich source of secondary metabolites, mainly polypohenols and triterpenoids. About 39 species have been phytochemically studied leading to the identification of 368 compounds. This work involves the use of hyphenated mass spectrometric methods such as HPLC-ESI-QTOF-MS/MS and UPLC-ESI-QqQLIT-MS/MS for qualitative and quantitative analysis of major bioactive constituents in selected medicinal plants without isolation. It also describes the methods of mass fingerprinting and their use to investigate the plant species variations with the help of statistical software’s (PCA). Markers were identified for quality control and authentications.
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Specificații

ISBN-13: 9781032019499
ISBN-10: 1032019492
Pagini: 154
Ilustrații: 18
Dimensiuni: 138 x 216 mm
Greutate: 0.29 kg
Ediția:1
Editura: CRC Press
Colecția CRC Press
Seria Phytochemical Investigations of Medicinal Plants

Locul publicării:Boca Raton, United States

Public țintă

Academic, Postgraduate, and Professional

Cuprins

Contents
List of figures    vii
List of tables    ix
Preface    xi
Acknowledgments    xiii
Authors    xv
List of abbreviations and units    xvii
1      Terminalia: Ethno- and Phytopharmacological Review    1
2      Identification of Bioactive Phytoconstituents
          of Terminalia Species by HPLC-ESI-QTOF- MS/MS    43
3      Quantification of Phenolic Compounds in Six Terminalia
          Species by UPLC-QqQLIT-MS/MS    89
4       Simultaneous Estimation of Phytoconstituents
          in T. chebula Fruit and Its Marketed Polyherbal Formulations    107
References 115
Index 133

Notă biografică

Dr. Brijesh Kumar is a Professor (AcSIR) and Chief Scientist of sophisticated analytical instrument facility division, CSIR-Central Drug Research Institute Lucknow, India. He has completed his PhD from CSIR-CDRI Lucknow (Dr. RML Avadh University Faizabad UP, India).Currently he is facility in charge at Sophisticated Analytical Instrument Facility (SAIF) division of CSIR-CDRI. He has to his credit more than 7 book chapters, three book and 145 papers in International journal of repute. His current area of research is applications of Mass Spectrometry tools (DART MS/Q-TOF LC-MS/4000 Q Trap LC-MS/ Orbitrap MSn) for qualitative and quantitative analysis molecules for quality control and authentication/standardization of Indian medicinal plants/parts and their herbal formulations. He is also involved in identification of marker compounds using statistical software to check adulteration/substitution.
Dr. Awantika Singh completed her PhD from the Academy of Scientific and Innovative Research (AcSIR), New Delhi, India and carried her research work under supervision of Dr. Brijesh Kumar at CSIR-Central Drug research Institute (CDRI) Lucknow. Her research includes development and validation of LC-MS/MS methods for qualitative and quantitative analysis of phytochemicals in Indian medicinal plants.
Dr. K. P. Madhusudanan is a mass spectrometry scientist born in 1947 in Kerala, India. He obtained his doctoral degree in 1975 specializing in Organic Mass Spectrometry in National Chemical Laboratory, Pune, India. He worked as a scientist and Head, Sophisticated Analytical Instrument Facility in Central Drug Research Institute, Lucknow until 2007. His research experience since 1970 includes various aspects of organic mass spectrometry such as fragmentation mechanism, gas phase unusual reactions, positive and negative ion mass spectrometry of natural products using various ionization techniques including DART, effects of metal cationization, LC/MS and MS/MS applications and quantitative analysis of drugs and metabolites. He authored more than 150 research publications. He was a member of the editorial board of Journal of Mass Spectrometry during 1995-2007. He is a fellow of the National Academy of Sciences, Allahabad, India. At present he lives in Kochi.

Descriere

Genus Terminalia is known to be a rich source of secondary metabolites, mainly polypohenols and triterpenoids. About 39 species have been phytochemically studied leading to the identification of 368 compounds.