This volume contains the papers of the 1st Workshop IFToMM for Sustainable Development Goals (I4SDG), held online on November 25-26, 2021. The main topics of the workshop include the aspects of theory, design and practice of mechanism and machine science which are instrumental in reaching a sustainable development, such as: biomechanical engineering, sustainable energy systems, robotics and mechatronics, green tribology, computational kinematics, dynamics of machinery, industrial applications of mechanism design, gearing and transmissions, multibody dynamics rotor dynamics, vibrations, humanitarian engineering, and socio-technical systems for sustainable and inclusive development. The contributions, which were selected by means of a rigorous international peer-review process, highlight numerous exciting ideas that will spur novel research directions and foster multidisciplinary collaboration among different specialists, demonstrating that medical and service robotics will drive the technological and societal change in the coming decades.