This book contains the works connected with the key advances in Intelligent Information Technologies for Industry presented in the main track of IITI 2022, the Sixth International Scientific Conference on Intelligent Information Technologies for Industry held on October 31 - November 6, 2022, in Istanbul, Turkey. The works were written by the experts in the field of artificial intelligence including topics such as machine learning, decision making intelligent systems, fuzzy logic, bioinspired systems and Bayesian networks. The following industrial application domains were touched: railway automation, intelligent medical systems, flexible socio-technical systems, navigation systems and energetic systems. The editors believe that this book will be helpful for all scientists and engineers interested in the modern state of applied artificial intelligence.