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Progress in Medicinal Chemistry: Progress in Medicinal Chemistry, cartea 56

David R. Witty, Brian Cox
en Limba Engleză Hardback – 19 mar 2017
Progress in Medicinal Chemistry, Volume 56 provides a review of eclectic developments in medicinal chemistry. This volume includes chapters covering recent advances in cancer therapeutics, fluorine in medicinal chemistry, a perspective on the next generation of antibacterial agents derived by manipulation of natural products, a potential new era for Chagas Disease drug discovery, and imaging in drug development. Specific chapters cover timely topics, such as the development of LRRK2 inhibitors for the treatment of Parkinson's, and recent discoveries and developments in TRPA1 modulators.
Users will find a comprehensive resource on the topic of medicinal chemistry that also discusses avenues for the acceleration of drug discovery programs.


  • Extended, timely reviews of topics in medicinal chemistry
  • Contains targets and technologies relevant to the discovery of tomorrow’s drugs
  • Presents analyses of successful drug discovery programs
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Specificații

ISBN-13: 9780444639394
ISBN-10: 044463939X
Pagini: 174
Dimensiuni: 152 x 229 mm
Greutate: 0.43 kg
Editura: ELSEVIER SCIENCE
Seria Progress in Medicinal Chemistry


Public țintă

Everyone interested in the strategy and practice of the preclinical phases of the creation of new medicines. Those wishing to understand the drivers of drug design or expand their knowledge of therapeutic target classes

Cuprins

1. Enabling Chemistry Technologies and Parallel Synthesis—Accelerators of Drug Discovery ProgramsS.W. Djuric, A.R. Bogdan, H.F. Koolman, Y. Wang and A. Vasudevan2. Development of LRRK2 Inhibitors for the Treatment of Parkinson’s DiseaseK.V. Christensen, G.P. Smith and D.S. Williamson3. Recent Progress in the Discovery and Development of TRPA1 ModulatorsS. Skerratt4. Small Molecule Inhibition of Interleukin–1 Receptor-Associated Kinase 4 (IRAK4)N.E. Genung and K. Guckian