Cantitate/Preț
Produs

Protein Targeting Compounds: Prediction, Selection and Activity of Specific Inhibitors: Advances in Experimental Medicine and Biology, cartea 917

Editat de Thomas Böldicke
en Limba Engleză Hardback – 6 iun 2016
This book presents an overview of the most relevant protein knockdown techniques. Readers will find a description of the generation and use of recombinant human antibodies, ER intrabodies and peptides as well as a description of the working mechanism and potential of the inhibitory action of each of these molecules. The book will also describe the selection and activity of a number of phosphatases, aptamers and allosteric modulators, focusing on A G protein coupled receptors. The book starts with a chapter on the in silico prediction of target-inhibitor interactions.
Key aspects of this book are:
- Selection strategies for monoclonal and recombinant human antibodies
- Selection strategies for ER intrabodies, peptides and aptamers
- Examples of the most efficient inhibitors and their applications in protein biochemistry and cell biology - Antibodies for cancer therapy and inhibitors of angiogenesis.
The book will be of great interest to scientists and students working in the life sciences on all areas related to protein biology. The variety of methods to modulate the activities of specific proteins which are introduced here will be of great benefit to the reader who is interested in general protein research or to readers who have very specific protein related questions.
Citește tot Restrânge

Toate formatele și edițiile

Toate formatele și edițiile Preț Express
Paperback (1) 98029 lei  39-44 zile
  Springer International Publishing – 30 mai 2018 98029 lei  39-44 zile
Hardback (1) 104641 lei  3-5 săpt.
  Springer International Publishing – 6 iun 2016 104641 lei  3-5 săpt.

Din seria Advances in Experimental Medicine and Biology

Preț: 104641 lei

Preț vechi: 110148 lei
-5% Nou

Puncte Express: 1570

Preț estimativ în valută:
20030 21536$ 16698£

Carte disponibilă

Livrare economică 28 noiembrie-12 decembrie

Preluare comenzi: 021 569.72.76

Specificații

ISBN-13: 9783319328041
ISBN-10: 3319328042
Pagini: 288
Ilustrații: VIII, 288 p. 49 illus., 31 illus. in color.
Dimensiuni: 155 x 235 x 23 mm
Greutate: 0.68 kg
Ediția:1st ed. 2016
Editura: Springer International Publishing
Colecția Springer
Seria Advances in Experimental Medicine and Biology

Locul publicării:Cham, Switzerland

Cuprins

Introduction.- Part I Methods of Structure Prediction.- Chapter 1 In Silico Prediction of Target-Inhibitor Interactions.- Part II Antibodies.- Chapter 2 Antibodies and Selection of Monoclonal Antibodies.- Chapter 3 Selection of Recombinant Human Antibodies.- Chapter 4 Selection of Recombinant Human Antibodies against Toxins and Viruses.- Chapter 5 Recent Advances with ER Targeted Intrabodies.- Chapter 6 Therapeutic Blocking Antibodies against Oncogenic Receptors and Growth Factors.- Chapter 7 Synthetic Cystine-Knot Miniproteins-Valuable Scaffolds for Polypeptide Engineering.- Part III Peptides, Small Molecules and Aptamers.- Chapter 8 Peptides and Peptide Analogs to Inhibit Protein.- Chapter 9 Allosteric Modulators of the Class A G Protein coupled Receptors.- Chapter 10 Phosphatases: Their Roles in Cancer and their Chemical Modulators.- Chapter 11 Selection and Application of Aptamers and Intramers.- Part IV Angiogenesis Inhibitors.- Chapter 12 Inhibitors of Angiogenesis.

Textul de pe ultima copertă

This book presents an overview of the most relevant protein knockdown techniques. Readers will find a description of the generation and use of recombinant human antibodies, ER intrabodies and peptides as well as a description of the working mechanism and potential of the inhibitory action of each of these molecules. The book will also describe the selection and activity of a number of phosphatases, aptamers and allosteric modulators, focusing on A G protein coupled receptors. The book starts with a chapter on the in silico prediction of target-inhibitor interactions.
Key aspects of this book are:
- Selection strategies for monoclonal and recombinant human antibodies
- Selection strategies for ER intrabodies, peptides and aptamers
- Examples of the most efficient inhibitors and their applications in protein biochemistry and cell biology - Antibodies for cancer therapy and inhibitors of angiogenesis.
The book will be of great interest to scientists and students working in the life sciences on all areas related to protein biology. The variety of methods to modulate the activities of specific proteins which are introduced here will be of great benefit to the reader who is interested in general protein research or to readers who have very specific protein related questions.

Caracteristici

A comprehensive overview of strategies for the generation of protein inhibitors Covering prediction, selection and the biological application of protein inhibitors Extensive discussion of future approaches and applications of protein inhibitors