Cantitate/Preț
Produs

Regenerative Medicine for Degenerative Muscle Diseases: Stem Cell Biology and Regenerative Medicine

Editat de Martin K. Childers
en Limba Engleză Hardback – 19 dec 2015
This book compiles andexplores cutting-edge research in degenerative skeletal disorders, such asDuchenne muscular dystrophy and congenital myopathy, and new stem-cell basedtherapies and gene replacement therapy. Twelve expertly-authored chapters navigatethe nuances of these treatments in an array of contexts and biological systems.The topics covered include: How are urine cells from a patient with Duchennemuscular dystrophy transformed into beating heart cells? What can reprogrammedcells tell us about heart muscle failure? What do gene mutations mean for thoseborn with a muscle disease? How are manufacturing methods applied to human stemcells? Does therapeutic exercise benefit those patients who receive engineeredlimb muscle? Is there practical advice about nutrition to enhance musclefunction for the Duchenne patient? Can microRNAs be useful to regeneratediseased muscle?
 RegenerativeMedicine for Degenerative Muscle Diseases is ideal for scientistsand clinicians from varying disciplines in genetics, cell biology, virology,cell-based manufacturing, rehabilitation medicine, nutrition, veterinarymedicine and neurosurgery. The reader will see how transformative changes occurin medicine that can powerfully impact the future for patients suffering frominherited disorders affecting muscles of the body, including the heart.
Citește tot Restrânge

Toate formatele și edițiile

Toate formatele și edițiile Preț Express
Paperback (1) 93120 lei  6-8 săpt.
  Springer – 29 mar 2019 93120 lei  6-8 săpt.
Hardback (1) 64462 lei  6-8 săpt.
  Springer – 19 dec 2015 64462 lei  6-8 săpt.

Din seria Stem Cell Biology and Regenerative Medicine

Preț: 64462 lei

Preț vechi: 75837 lei
-15% Nou

Puncte Express: 967

Preț estimativ în valută:
12340 12691$ 10238£

Carte tipărită la comandă

Livrare economică 20 februarie-06 martie

Preluare comenzi: 021 569.72.76

Specificații

ISBN-13: 9781493932276
ISBN-10: 1493932276
Pagini: 336
Ilustrații: XIII, 336 p. 26 illus., 23 illus. in color.
Dimensiuni: 155 x 235 x 21 mm
Greutate: 0.67 kg
Ediția:1st ed. 2016
Editura: Springer
Colecția Humana
Seria Stem Cell Biology and Regenerative Medicine

Locul publicării:New York, NY, United States

Public țintă

Professional/practitioner

Cuprins

Preface.- 1. Regenerative Medicine Approaches to Degenerative Muscle Diseases.- 2. An Overview of rAAV Vector Product Development for Gene Therapy.- 3. Gene Discovery in Congenital Myopathy.- 4. Stem Cell Transplantation for Degenerative Muscle.- 5. Spinal Cord Cellular Therapeutics Delivery:  Device Design Considerations.- 6. Patient Derived Induced Pluripotent Stem Cells Provide a Regenerative Medicine Platform for Duchenne Muscular Dystrophy Heart Failure.- 7. Overview of Chemistry, Manufacturing and Controls (CMC) for Pluripotent Stem Cell-Based Therapies.- 8. Regenerative Rehabilitation: Synergizing Regenerative Medicine Therapies with Rehabilitation for Improved Muscle Regeneration in Muscle Pathologies.- 9. Practical Nutrition Guidelines for Individuals with Duchenne Muscular Dystrophy.- 10. Identifying Beneficial Drug Therapies for Muscle Disease Using Zebrafish.- 11. The Use of miRNAs in Muscle Diseases.- 12 Canine Inherited Dystrophinopathies and Centronuclear Myopathies.- Index.

Notă biografică

Martin K. (Casey) Childers, D.O., Ph.D.  is a professor in the Department of Rehabilitation Medicine and Investigator at the Institute for Stem Cell & Regenerative Medicine, University of Washington. He is a graduate of Seattle Pacific University  (B.A., Music Performance), Western University (D.O., Medicine, Osteopathic) and The University of Missouri (Ph.D., Physiology & Pharmacology; residency, Rehabilitation Medicine). The Childers' laboratory works in two areas of investigation. In a series of preclinical studies, they address the hurdles required for systemic gene replacement delivery for patients with X-Linked Myotubular Myopathy (XLMTM). In other studies, they use a "disease in a dish" approach with induced pluripotent stem (iPS) cells to study heart disease in patients with Duchenne muscular dystrophy (DMD). Dr. Childers clinical medicine practice at the University of Washington Medical Center is dedicated to serve patients with neuromuscular diseases.

Textul de pe ultima copertă

This book compiles andexplores cutting-edge research in degenerative skeletal disorders, such asDuchenne muscular dystrophy and congenital myopathy, and new stem-cell basedtherapies and gene replacement therapy. Twelve expertly-authored chapters navigatethe nuances of these treatments in an array of contexts and biological systems.The topics covered include: How are urine cells from a patient with Duchennemuscular dystrophy transformed into beating heart cells? What can reprogrammedcells tell us about heart muscle failure? What do gene mutations mean for thoseborn with a muscle disease? How are manufacturing methods applied to human stemcells? Does therapeutic exercise benefit those patients who receive engineeredlimb muscle? Is there practical advice about nutrition to enhance musclefunction for the Duchenne patient? Can microRNAs be useful to regeneratediseased muscle?
 RegenerativeMedicine for Degenerative Muscle Diseases is ideal for scientistsand clinicians from varying disciplines in genetics, cell biology, virology,cell-based manufacturing, rehabilitation medicine, nutrition, veterinarymedicine and neurosurgery. The reader will see how transformative changes occurin medicine that can powerfully impact the future for patients suffering frominherited disorders affecting muscles of the body, including the heart.

Caracteristici

Examines new and developing regenerative medicine enabling technologies for the treatment of patients with degenerative diseases of skeletal muscle Provides a rapid look at new approaches to old conditions that impact thousands of patients and their families worldwide Presents a new regenerative medicine approach to treatment or discovery