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Retinoid Signaling Pathways de Ehmke Pohl

Retinoid Signaling Pathways: Methods in Enzymology, cartea 637

Ehmke Pohl
en Limba Engleză Hardback – 29 apr 2020
Retinoid Signaling Pathways, Volume 637, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Sections in this release include The chemistry and biochemistry of Vitamin A and its natural derivative, Biosynthesis of retinoic acids, Biodegration of retinoic acids mediated by retinoid binding proteins, Retinoic acid homeostasis, Cryo Electron Microscopy to study retinol update via the STRA6 receptor, Immuno-detection of retinoic acid synthesis enzymes in the brain, classical pathway of gene regulation by retinoids, Protein-protein interactions in the regulation of retinoid acid receptors activity, and much more.


  • Provides the authority and expertise of leading contributors from an international board of authors
  • Presents the latest release in the Methods in Enzymology series
  • Includes the latest information on retinoid signaling pathways
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Specificații

ISBN-13: 9780128201442
ISBN-10: 0128201444
Pagini: 610
Dimensiuni: 152 x 229 mm
Greutate: 0.98 kg
Editura: ELSEVIER SCIENCE
Seria Methods in Enzymology

Public țintă

Biochemists, biophysicists, molecular biologists, analytical chemists, and physiologists.

Cuprins

    1. Vitamin A and its natural derivativesChris P.F. Redfern
    2. Post-natal all-trans-retinoic acid biosynthesisJoseph L. Napoli
    3. Retinoid metabolism and functions mediated by retinoid binding-proteinsJoseph L. Napoli and Hong Sik Yoo
    4. Generation and isolation of recombinant retinoid oxidoreductase complexMark K. Adams, Olga V. Belyaeva and Natalia Y. Kedishvili
    5. Sample preparation for structural and functional analyses of the STRA6 receptor for retinol-binding proteinBrianna K. Costabile, Youn-Kyung Kim, Yunting Chen, Oliver B. Clarke, Loredana Quadro and Filippo Mancia
    6. Use of fixatives for immunohistochemistry and their application for detection of retinoic acid synthesizing enzymes in the central nervous systemAzita Kouchmeshky and Peter McCaffery
    7. Classical pathways of gene regulation by retinoidsEhmke Pohl and Charles W.E. Tomlinson
    8. Protein-protein interactions in the regulation of RAR–RXR heterodimers transcriptional activityAlbane le Maire, Pierre Germain and William Bourguet
    9. Natural ligands of RXR receptorsPatricia García, Paula Lorenzo and Angel R. de Lera
    10. DNA recognition by retinoic acid nuclear receptorsCarole Peluso-Iltis, Judit Osz and Natacha Rochel
    11. Noncanonical retinoic acid signalingJennifer Nhieu, Yu-Lung Lin and Li-Na Wei
    12. Retinoic acid and microRNALijun Wang, Atharva Piyush Rohatgi and Yu-Jui Yvonne Wan
    13. Analysis of vitamin A and retinoids in biological matricesLindsay C. Czuba, Guo Zhong, King Yabut and Nina Isoherranen
    14. Effects of vitamin A and retinoic acid on mouse embryonic stem cells and their differentiating progenyMary Ann Asson-Batres and Christopher W. Norwood
    15. Identifying vitamin A signaling by visualizing gene and protein activity, and by biochemical isolation of vitamin A metabolitesStephen R. Shannon, Jianshi Yu, Amy E. Defnet, Danika Bongfeldt, Alexander R. Moise, Maureen A. Kane and Paul A. Trainor
    16. Whole mount in situ hybridization and immunohistochemistry for studying retinoic acid signaling in developing amphioxusMatteo Bozzo, Simona Candiani and Michael Schubert
    17. Design of synthetic retinoidsDavid R. Chisholm and Andrew Whiting
    18. Application of human organotypic skin raft cultures for analysis of retinoid metabolism, retinoic acid signaling, and screening of bioactive rexinoidsAlla V. Klyuyeva, Kelli R. Goggans, Natalia Y. Kedishvili and Olga V. Belyaeva
    19. Tissue localization of retinoic acid receptor (RAR) active drugsAzita Kouchmeshky, Timothy Goodman, Andy Whiting and Peter McCaffery
    20. The development of methodologies for high-throughput retinoic acid binding assays in drug discovery and beyondCharles W.E. Tomlinson and Andrew Whiting
    21. Using the human CYP26A1 gene promoter as a suitable tool for the determination of RAR-mediated retinoid activity
Reza Zolfaghari, Floyd J. Mattie, Cheng-Hsin Wei, David R. Chisholm, Andrew Whiting and A. Catharine Ross