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The Kappa Opioid Receptor de Lee-Yuan Liu-Chen

The Kappa Opioid Receptor: Handbook of Experimental Pharmacology, cartea 271

Editat de Lee-Yuan Liu-Chen, Saadet Inan
en Limba Engleză Paperback – 26 noi 2022
This book covers the latest knowledge in structure, signaling, and biochemical pharmacology of KOR as well as preclinical research and clinical applications (including clinical phase studies and approved for human use) of KOR compounds. It is divided up into the three parts: Molecular aspects of KOR, Preclinical research on pharmacology of KOR agonists and antagonists in animals and KOR agonists and antagonists in clinical use and in past and present clinical trials.

The chapters "Biosensors monitor ligand-selective effects at kappa opioid receptors" and "The role of dynorphin and the kappa opioid receptor in schizophrenia and major depressive disorder: a translational approach" of this book are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.


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Specificații

ISBN-13: 9783030890766
ISBN-10: 3030890767
Pagini: 577
Ilustrații: XI, 577 p. 100 illus., 30 illus. in color.
Dimensiuni: 155 x 235 mm
Ediția:1st ed. 2022
Editura: Springer International Publishing
Colecția Springer
Seria Handbook of Experimental Pharmacology

Locul publicării:Cham, Switzerland

Cuprins

From the contents. Preface.-Part I: Molecular aspects of KOR.- Part II: Preclinical research on pharmacology of KOR agonists and antagonists in animals.- Part III: KOR agonists and antagonists in clinical use and in past and present clinical trials.

Textul de pe ultima copertă

This book covers the latest knowledge in structure, signaling, and biochemical pharmacology of KOR as well as preclinical research and clinical applications (including clinical phase studies and approved for human use) of KOR compounds. It is divided up into the three parts: Molecular aspects of KOR, Preclinical research on pharmacology of KOR agonists and antagonists in animals and KOR agonists and antagonists in clinical use and in past and present clinical trials.

The chapters "Biosensors monitor ligand-selective effects at kappa opioid receptors" and "The role of dynorphin and the kappa opioid receptor in schizophrenia and major depressive disorder: a translational approach" of this book are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Caracteristici

Provides recent advances in kappa opioid receptor (KOR) structure and signaling Highlights advancements in preclinical research on KOR agonists and antagonists in experimental animal models Summarizes development of KOR agonists/antagonists for clinical use (chronic itch, substance abuse, psych. diseases)