In this issue of Nursing Clinics of North America, guest editor Dr. Brent MacWilliams of the University of Wisconsin College of Nursing brings his considerable expertise to the topic of Trends in Men's Health. Men in the U.S. have higher lifetime risks for heart disease, cancer, diabetes, HIV/AIDS, suicide, liver disease, and additional morbidities than women. In addition, men have a general reluctance to seek help from physicians, are less likely than women to be aware of disease symptoms, use primary care services less frequently than women, and experience suicide rates nearly four times higher than women. In this issue, top experts in the field provide useful clinical information to bedside nurses while providing important updates in the areas of men's health.