Using Mass Spectrometry for Drug Metabolism Studies
Editat de Walter A. Korfmacheren Limba Engleză Paperback – 15 oct 2019
The stand-alone chapters cover various topics – from metabolite identification to fast chromatography with UPLC – and in a style that is understandable to experts and field newcomers alike. The second edition of this bestseller includes coverage of new instrumentation and software as well as a wealth of updated information on the latest findings surrounding biomarkers and metabolomics and new chapters on both UPLC and DESI/DART.
With more than 180 illustrations and an eight-page color insert, this valuable reference explores multiple modern mass spectrometry techniques and strategies. It includes an excellent overview of the entire drug discovery process plus the latest developments on how mass spectrometry is used to support this endeavor.
Toate formatele și edițiile | Preț | Express |
---|---|---|
Paperback (1) | 377.34 lei 6-8 săpt. | |
CRC Press – 15 oct 2019 | 377.34 lei 6-8 săpt. | |
Hardback (1) | 1187.22 lei 6-8 săpt. | |
CRC Press – 3 noi 2009 | 1187.22 lei 6-8 săpt. |
Preț: 377.34 lei
Preț vechi: 481.24 lei
-22% Nou
Puncte Express: 566
Preț estimativ în valută:
72.21€ • 74.50$ • 61.12£
72.21€ • 74.50$ • 61.12£
Carte tipărită la comandă
Livrare economică 04-18 martie
Preluare comenzi: 021 569.72.76
Specificații
ISBN-13: 9780367384951
ISBN-10: 0367384957
Pagini: 451
Dimensiuni: 156 x 234 mm
Greutate: 0.83 kg
Ediția:2
Editura: CRC Press
Colecția CRC Press
ISBN-10: 0367384957
Pagini: 451
Dimensiuni: 156 x 234 mm
Greutate: 0.83 kg
Ediția:2
Editura: CRC Press
Colecția CRC Press
Public țintă
Academic and Professional Practice & DevelopmentCuprins
Strategies and Techniques for Bioanalytical Assays as Part of New Drug Discovery. The Drug Discovery Process: From Molecules to Drugs. PK Principles and PK/PD Applications. Mass Spectrometry for In Vitro ADME Screening. Metabolite Identification Strategies and Procedures. Reactive Metabolite Screening and Covalent-Binding Assays. Fast Metabolite Screening in a Discovery Setting. Fast Chromatography with UPLC and Other Techniques. Supercritical Fluid Chromatography–Mass Spectrometry. Biomarkers of Efficacy and Toxicity: Discovery and Assay. Imaging Mass Spectrometry for Small Molecules. MALDI IMS for Proteins and Biomarkers. Ambient Ionization Methods and Their Early Applications in ADME Studies. Pharmaceutical Applications of Accelerator Mass Spectrometry.
Descriere
The first edition of this now classic work helped establish mass spectrometry as the premier tool for drug metabolism studies. Keeping pace with rapid advances, the emergence of new approaches, and increasing demands by vendors, the second edition of this bestseller includes cutting-edge coverage of new instrumentation and software as well as significant new information on the latest findings regarding biomarkers and metabolomics. In addition to exploring all modern techniques and strategies, it offers an excellent overview of the entire drug discovery process, including the latest developments in molecular research.