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Biodrug Delivery Systems: Fundamentals, Applications and Clinical Development de Mariko Morishita

Biodrug Delivery Systems: Fundamentals, Applications and Clinical Development: Drugs and the Pharmaceutical Sciences

Editat de Mariko Morishita, Kinam Park
en Limba Engleză Hardback – 10 dec 2009
Biodrug Delivery Systems: Fundamentals, Applications and Clinical Development presents the work of an international group of leading experts in drug development and biopharmaceutical science who discuss the latest advances in biodrug delivery systems and associated techniques. The book discusses components of successful formulation, delivery, and production of biodrugs, which include sophisticated plants and complex processes, a well-trained and knowledgeable staff, and proper quality control. In addition, the authors examine:
  • ADME (Absorption, Metabolism, Distribution, and Elimination of biodrugs)
  • Directing and influencing the successful development of currently marketed best-selling biodrugs
  • Routes of administration
  • Mechanisms of biodrug absorption
  • Alternative possibilities for drug delivery routes
  • Formulationson the market from the perspective of industry personnel involved in biodrug development
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Specificații

ISBN-13: 9781420086683
ISBN-10: 1420086685
Pagini: 488
Ilustrații: 90 b/w images
Dimensiuni: 152 x 229 x 32 mm
Greutate: 0.77 kg
Ediția:New.
Editura: CRC Press
Colecția CRC Press
Seria Drugs and the Pharmaceutical Sciences

Locul publicării:Boca Raton, United States

Public țintă

Academic, Professional, and Professional Practice & Development

Cuprins

1. Overview of Biodrug delivery system. 2. Issues in Biodrug delivery system. 3. Pharmacokinetic consideration of Biodrugs. Specific Route of Delivery. 1. Parenteral delivery. 2. Brain delivery. 3. Ocular delivery. 4. Nasal delivery. 5. Buccal delivery. 6. Pulmonary delivery. 7. Transdermal delivery. 8. Colon delivery. 9. Oral delivery. 10. Cellular delivery. Delivery Systems. 1. Targeting: PK consideration. Monoclonal antibody. Receptor-mediated endocytosis. 2. Bioadhesive delivery system. 3. Modified release delivery system. 4. Nanoparticulate delivery system. 5. Lipid-based delivery system. 6. Implantable delivery system. 7. Modifying the physiochemical nature of Biodrugs. 8. Regulatory perspective of Biodrug development. Development of Biodrug Products. 1. Leuplin. 2. ANP (atrial natriuretic peptide). 3. Amylin and GLP-1 agonists. 4. GHRP-2 (growth hormone releasing peptide. 5. Endothelin receptor antagonist. 6. Angiotensin II receptor antagonist. 7. Insulin (inhalation). 8. Calcitonin (nasal, etc.). 9. Sandstatin LAR. 10. Interferon. 11. Vaccine. Perspective of Biodrug Products.

Descriere

An international group of leading experts in drug development and biopharmaceutical science discusses the latest advances in biodrug delivery systems and associated techniques.