In this issue of Veterinary Clinics: Small Animal Practice, guest editors Drs. Maxey L. Wellman and M. Judith Radin bring their considerable expertise to the topic of Clinical Pathology. Evaluation of clinical laboratory data is used daily in the diagnosis and monitoring of veterinary patients, and the field is rapidly expanding as new tests and technologies become available. This issue provides valuable, up-to-date information on current important topics in clinical pathology that are of interest to clinicians, veterinary students, and residents.