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Developmental and Reproductive Toxicology de Ali S. Faqi

Developmental and Reproductive Toxicology: Methods in Pharmacology and Toxicology

Editat de Ali S. Faqi
en Limba Engleză Hardback – 18 aug 2017
This meticulous volume covers metabolism and drug-drug interactions during pregnancy, critical periods of developmental toxicology, in vivo and alternative methods to assess potential developmental toxicity for drugs and chemicals, and effects of chemicals on testes and mammary glands. Evaluation of developmental and reproductive toxicology endpoints is an integral part of the safety assessment process for compounds with potential use in women of childbearing age or females that might be exposed during pregnancy as well as men of reproductive potential. The in vivo assessments included here are guideline-driven and are required for submissions for product approval. Written for the Methods in Pharmacology and Toxicology series, this collection includes the kind of detailed implementation advice necessary for success in the lab. 

Authoritative and practical, Developmental and Reproductive Toxicology is an ideal resource for researchers working
in this vital field of study.
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Specificații

ISBN-13: 9781493972067
ISBN-10: 1493972065
Pagini: 150
Ilustrații: XII, 314 p. 24 illus., 17 illus. in color.
Dimensiuni: 178 x 254 x 20 mm
Greutate: 0.79 kg
Ediția:1st ed. 2017
Editura: Springer
Colecția Humana
Seria Methods in Pharmacology and Toxicology

Locul publicării:New York, NY, United States

Cuprins

Metabolism and Drug-Drug Interaction in Pregnant Mother/Placenta/Fetus.- Critical Periods of Development in Teratology.- Nonclinical Safety Assessment of Developmental and Reproductive Toxicology: Considerations for Conducting Fertility, Embryo-Fetal Development, and Pre- and Postnatal Developmental Toxicology Studies.- A Developmental and Reproductive Toxicology Program for Chemical Registration.- The Influence of Environmental Contaminants and Lifestyle on Testicular Damage and Male Fertility.- Effects of Chemicals on Mammary Gland Development.- Alternative Methods Used to Assess Potential Embryo-Fetal Developmental Risk of Pharmaceuticals.- Using the Alternative Model C. elegans in Reproductive and Developmental Toxicology Studies.- High-Throughput Screens for Embryonic Stem Cells: Stress-Forced Potency-Stemness Loss Enables Toxicological Assays.

Textul de pe ultima copertă

This meticulous volume covers metabolism and drug-drug interactions during pregnancy, critical periods of developmental toxicology, in vivo and alternative methods to assess potential developmental toxicity for drugs and chemicals, and effects of chemicals on testes and mammary glands. Evaluation of developmental and reproductive toxicology endpoints is an integral part of the safety assessment process for compounds with potential use in women of childbearing age or females that might be exposed during pregnancy as well as men of reproductive potential. The in vivo assessments included here are guideline-driven and are required for submissions for product approval. Written for the Methods in Pharmacology and Toxicology series, this collection includes the kind of detailed implementation advice necessary for success in the lab. 

Authoritative and practical, Developmental and Reproductive Toxicology is an ideal resourc
e for researchers working in this vital field of study.

Caracteristici

Features in vivo assessments that are guideline-driven and required for submissions for product approval Covers a variety of toxicological issues in both male and female reproductive systems Provides vital procedures for the study of phamaceutical safety assessment Includes supplementary material: sn.pub/extras