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Immunotherapy and Biomarkers in Neurodegenerative Disorders: Methods in Pharmacology and Toxicology

Editat de Martin Ingelsson, Lars Lannfelt
en Limba Engleză Hardback – 14 apr 2016
This practical volume examines a number of topicsthat explore the current status of immunotherapy and diagnostic markers forneurodegenerative disorders. With a focus on Alzheimer’s disease, the firstsections of the book examine immunotherapeutic approaches for theaforementioned disease as well as for Parkinson’s disease and Huntington’s disease,amongst others. The last section of the book covers the importance of biomarkertechniques to catch these diseases early enough for the treatments to be mostuseful. Written for the Methods inPharmacology and Toxicology series, this book contains the kind of detaileddescriptions and implementation advice that will offer a smooth transition intothe lab.
Authoritative and useful, Immunotherapy and Biomarkers inNeurodegenerative Disorders aims to aid in the continued progress in thedevelopment of novel immune-based drugs and diagnostic tools for thesedevastating brain diseases.
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Specificații

ISBN-13: 9781493935581
ISBN-10: 1493935585
Pagini: 290
Ilustrații: X, 289 p. 40 illus., 32 illus. in color.
Dimensiuni: 178 x 254 x 18 mm
Greutate: 0.74 kg
Ediția:1st ed. 2016
Editura: Springer
Colecția Humana
Seria Methods in Pharmacology and Toxicology

Locul publicării:New York, NY, United States

Public țintă

Professional/practitioner

Cuprins

Immunotherapy Against Amyloid-β in Alzheimer’s Disease: AnOverview.- Active Immunization Against the Amyloid-β Peptide.- ImmunotherapyAgainst N-Truncated Amyloid-β Oligomers.- Immunotherapy Against Amyloid-βProtofibrils: Opportunities and Challenges.- Immunotherapy Against α-SynucleinPathology.- Extracellular α-Synuclein as a Target for Immunotherapy.- Immunotherapyof Parkinson’s Disease.- TauImmunotherapy.- Active and Passive Immunotherapy Against Tau: Effectsand Potential Mechanisms.- Immunotherapy on Experimental Models forHuntington’s Disease.- Cerebrospinal Fluid Biomarkers in Alzheimer’s Disease.- VolumetricMRI as a Diagnostic Tool in Alzheimer's Disease.- PET Imaging as a DiagnosticTool in Alzheimer´s Disease.- Αlpha-Synuclein as a Diagnostic Biomarker forParkinson’s Disease.- Imaging as a Diagnostic Tool in Parkinson’s Disease.- MassSpectrometry-Based Proteomics in Biomarker Discovery for NeurodegenerativeDiseases.

Textul de pe ultima copertă

This practical volume examines a number of topics that explore the current status of immunotherapy and diagnostic markers for neurodegenerative disorders. With a focus on Alzheimer’s disease, the first sections of the book examine immunotherapeutic approaches for the aforementioned disease as well as for Parkinson’s disease and Huntington’s disease, amongst others. The last section of the book covers the importance of biomarker techniques to catch these diseases early enough for the treatments to be most useful. Written for the Methods in Pharmacology and Toxicology series, this book contains the kind of detailed descriptions and implementation advice that will offer a smooth transition into the lab. 
Authoritative and useful, Immunotherapy and Biomarkers in Neurodegenerative Disorders aims to aid in the continued progress in the development of novel immune-based drugs and diagnostic tools for these devastating brain diseases.

Caracteristici

Includes cutting-edge techniques for the study of neurodegenerative disorders through immunotherapy and biomarker research Offers state-of-the-art contributions from renowned experts Features practical and vital implementation advice Includes supplementary material: sn.pub/extras