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Genetic Damage in Human Spermatozoa de Elisabetta Baldi

Genetic Damage in Human Spermatozoa: Advances in Experimental Medicine and Biology, cartea 791

Editat de Elisabetta Baldi, Monica Muratori
en Limba Engleză Hardback – 17 aug 2013
There are several types of damage that can be found in the male gamete. Genetic damage in spermatozoa can originate during spermatogenesis, or it can originate during transit in both male and female genital tracts. Damage can also be due to ageing, environmental or iatrogenic conditions, as well as to the protocols to cryopreserve and to select spermatozoa in assisted reproduction techniques. The purpose of this book is to provide a comprehensive resource for all possible DNA damages in sperm, the relation to fertility and infertility, and possible transgenerational heritable effects.
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Specificații

ISBN-13: 9781461477822
ISBN-10: 1461477824
Pagini: 185
Ilustrații: XIII, 195 p.
Dimensiuni: 155 x 235 x 15 mm
Greutate: 0.56 kg
Ediția:2013
Editura: Springer
Colecția Springer
Seria Advances in Experimental Medicine and Biology

Locul publicării:New York, NY, United States

Public țintă

Research

Cuprins

Structure of chromatin in spermatozoa.- Genomic changes in spermatozoa of aging male.- Chromosomal aberrations and aneuploidies.- The sperm epigenome: implications for the embryo.- Paternal reprogramming of genome: transgenerational effects.- Alterations in protamination.- Sperm DNA fragmentation and base oxidation.- Iatrogenic Genetic damage.- Sperm selection: effect on sperm DNA quality.- Effect of antioxidant treatments on sperm genetic damage.- Index.

Textul de pe ultima copertă

There are several types of damage that can be found in the male gamete. Genetic damage in spermatozoa can originate during spermatogenesis, or it can originate during transit in both male and female genital tracts. Damage can also be due to ageing, environmental or iatrogenic conditions, as well as to the protocols to cryopreserve and to select spermatozoa in assisted reproduction techniques. This book provides a comprehensive resource for all possible DNA damages in sperm, the relation to fertility and infertility, and possible transgenerational heritable effects.

Caracteristici

This book will cover all possible DNA damage in sperm The book will also discuss its relation to fertility and transgenerational heritable effects Chapter structure will include mechanisms of damage, consequences in reproduction, possibility to eliminate damage, and possible transgenerational heritable effects ?

Notă biografică

Dr. Baldi started to work in sperm biology in 1990, by studying several aspect of sperm functions as well as DNA damage. She published 155 publications in IF journals with peer review.  She has been invited as speaker in many National and International Congresses and Symposia.  She is currently associate professor of Clinical Pathology at the University of Florence and responsible of the Laboratory of semen analysis and semen cryopreservation of the Azienda Ospedaliera-Universitaria Careggi  
Dr. Muratori started to work in sperm biology in 1997, by mainly studying sperm DNA damage. She published 80 publications with IF journals with peer review. She has been invited as speaker in many National and International Congresses and Symposia.  She is currently researcher of Applied Technical and Medical Sciences at the University of Florence