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Green Approaches in Medicinal Chemistry for Sustainable Drug Design: Advances in Green and Sustainable Chemistry

Editat de Bimal Banik
en Limba Engleză Paperback – 26 mar 2020
Extensive experimentation and high failure rates are a well-recognised downside to the drug discovery process, with the resultant high levels of inefficiency and waste producing a negative environmental impact. Sustainable and Green Approaches in Medicinal Chemistry reveals how medicinal and green chemistry can work together to directly address this issue.
After providing essential context to the growth of green chemistry in relation to drug discovery in Part 1, the book goes on to identify a broad range of practical methods and synthesis techniques in Part 2. Part 3 reveals how medicinal chemistry techniques can be used to improve efficiency, mitigate failure and increase the environmental benignity of the entire drug discovery process, whilst Parts 4 and 5 discuss natural products and microwave-induced chemistry. Finally, the role of computers in drug discovery is explored in Part 6.


  • Identifies novel and cost effective green medicinal chemistry approaches for improved efficiency and sustainability
  • Reflects on techniques for a broad range of compounds and materials
  • Highlights sustainable and green chemistry pathways for molecular synthesis
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Specificații

ISBN-13: 9780128175927
ISBN-10: 0128175923
Pagini: 1044
Ilustrații: Approx. 200 illustrations
Dimensiuni: 152 x 229 mm
Greutate: 1.37 kg
Editura: ELSEVIER SCIENCE
Seria Advances in Green and Sustainable Chemistry


Public țintă

Medicinal Chemists, pharmaceutical scientists, Biotechnologists, Green Chemists and Environmental Chemists working in both academia and industry; Students in related fields; Scientists working in Government Research Agencies; Industrial Scientists starting from Entry Level Professionals to Vice President/President

Cuprins

Part 1: Green Chemistry

Green Chemistry Assisted Synthesis of Natural and Synthetic Compounds as Anticancer Agents
Antibacterial and Antimicrobial Coatings on Metal Substrate by Cold Spray Technique: Present and Future Perspectives
Graphene Oxide Nanosheets as Sustainable Carbocatalysts: Synthesis of Medicinally Important Heterocycles
Sustainable and Green Technologies for Synthesis of Potential Drugs Targeted Towards Tropical Diseases
Clay-Mediated Synthesis of Biologically Active Molecules: Green and Sustainable Approaches
The Role of Ionic Liquid in Medicinal Chemistry
Synthesis of Medicinally Important Heterocycles Inside the Nanoreactors Built in Non-conventional Reaction Media
Green Synthesis of Nanoparticles and Nanocomposites: Medicinal Aspects
Part 2: Methods and Synthesis

Use of Sustainable Organic Transformations in the Construction of Heterocyclic Scaffolds
One-Pot Synthesis of Medicinally Active Compounds
Organocatalytic Cycloaddition Reaction: A Gateway for Molecular Complexity
Diverse Synthesis of Steroids
Reactions in Water: Synthesis of Biologically Active Compounds
Solventless Reactions: Green and Sustainable Approaches in Medicinal Chemistry
Thiosugars in the Synthesis of Biologically Active Compounds
Part 3: Medicinal Chemistry

Implementing Green Chemistry for Synthesis of Cholesterol Lowering Statin Drugs
Sustainable Release of Nanodrugs: A New Biosafe Approach
Stimuli Responsive Sugar-Derived Hydrogels: A Modern Approach in Cancer Biology
Green Synthesis and Biological Evaluation of Anticancer Drugs
Green Chemistry and Synthetic Approaches in the Development of Antidepressant and Antipsychotic agents
Part 4: Natural Products

Natural Spices in Medicinal Chemistry: Properties and Benefits
Medicinal Plants and Their Compounds With Anticancer Properties

Part 5: Microwave-Induced Chemistry

Microwave-Assisted Synthesis of Anti-tubercular Agents: A Novel Approach
Microwave-Induced Synthesis of Steroids and Their Chemical Manipulations
Microwave-Induced Synthesis as a Part of Green Chemistry Approach for Novel Anti-inflammatory agents
Part 6: Computers in Drug Discovery

Dipole Moment of Medicinally Active Compounds: A Sustainable Approach
Computational Methods and Tools for Sustainable and Green Approaches in Drug Discovery