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Handbook of Pharmaceutical Granulation Technology: Drugs and the Pharmaceutical Sciences

Editat de Dilip M. Parikh
en Limba Engleză Paperback – 29 ian 2024
This fully revised edition of Handbook of Pharmaceutical Granulation Technology covers the rapid advances in the science of agglomeration,  process control, process modelling, scale-up, emerging particle engineering technologies, along with current regulatory changes presented by some of the prominent scientist and subject matter experts around the globe. Learn from more than 50 global subject matter experts who share their years of experience in areas ranging from drug delivery and pharmaceutical technology to advances in nanotechnology. Every pharmaceutical scientist should own a copy of this fourth edition resource.
Key Features:
  • Theoretical discussions covering granulation and engineering perspectives.
  • Covers new advances in expert systems, process modelling and bioavailability
  • Chapters on emerging technologies in particle engineering
  • Updated Current research and developments in granulation technologies
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Specificații

ISBN-13: 9780367741457
ISBN-10: 0367741458
Pagini: 904
Ilustrații: 734
Dimensiuni: 178 x 254 x 51 mm
Greutate: 1.61 kg
Ediția:4
Editura: CRC Press
Colecția CRC Press
Seria Drugs and the Pharmaceutical Sciences


Public țintă

Professional

Cuprins

1 Introduction  2 Theory of Granulation: An Engineering Perspective  3 Drug Substance and Excipient Characterization  4 Binders in Pharmaceutical Granulation  5 Excipients and their Attributes in Granulation  6 Spray Drying and Pharmaceutical Applications  7 Emerging Technologies for Particle Engineering  8 Roller Compaction Technology  9 Advances in Wet Granulation of Modern Drugs  10 Fluid Bed Granulation  11 Single Pot Processing  12 Extrusion/Spheronization as a Granulation Technique  13 Continuous Granulation  14 Effervescent Granulation  15 Granulation of Plant Products and Nutraceuticals  16 Granulation Approaches for Modified Release Products  17 Granulation of Poorly Water-Soluble Drugs  18 Granulation and Production Approaches of Orally Disintegrating Tablets  19 Melt Granulation  20 Sizing of Granulation  21 Granulation Characterization  22 Bioavailability and Granule Properties  23 Granulation Process Modeling  24 Scale-Up Considerations in Granulation  25 Advances in Process Controls and End-Point Determination  26 Use of Artificial Intelligence and Expert Systems in Pharmaceutical Applications  27 Regulatory Issues in Granulation: Leading Next Generation Manufacturing

Notă biografică

Dilip M. Parikh is President, DPharma Group Inc., Ellicott City, Maryland, USA. As a Chemical and pharmaceutical engineer, he has more than 45 years of experience in product developments and manufacturing, process engineering, operational management of various pharmaceutical facilities in Canada and the USA. He is an invited speaker globally on various solid dosage manufacturing technologies and troubleshooting, process optimization strategies, regulatory remediation, and PAT & QbD implementation strategies. The author of many scientific journal articles, book chapters, and the editor of first, the second and third edition of Handbook of Pharmaceutical Granulation Technology.

Descriere

This fully revised edition covers the rapid advances in the science of agglomeration,  process control, process modelling, scale-up, emerging particle engineering technologies, along with current regulatory changes presented by some of the prominent scientist and subject matter experts around the globe.