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Isocoumarin, Thiaisocoumarin and Phosphaisocoumarin: Natural Occurrences, Synthetic Approaches and Pharmaceutical Applications

Autor Sarbani Pal, Manojit Pal
en Limba Engleză Paperback – 26 oct 2018
Isocoumarin, Thiaisocoumarin and Phosphaisocoumarin: Natural Occurrences, Synthetic Approaches and Pharmaceutical Applications gives an overview of the various aspects of this class of heterocycle, with a major focus on synthesis and biological activity. Aromatic δ lactones or isocoumarins with thiaisocoumarins, phosphaisocoumarins and a-pyranone fused with a heteroaryl ring constitute an important class of heterocyclic compounds. This book provides the methods applied for the synthesis of thiaisocoumarins, phosphaisocoumarins, and a-pyranone fused with a heteroaryl ring. It is useful to medicinal and natural product chemists who want to synthesize target molecules and develop cutting-edge technologies to provide better solutions to researchers.


  • Features an overview of isocoumarins and their role in pharmaceutical research
  • Presents a template for the design, discovery and development of new and potential drugs in various therapeutic areas
  • Includes comprehensive coverage of the synthesis of isocoumarins, from traditional methods, to transition metal catalyzed methods
  • Looks at future applications for these important compounds in the areas of drug discovery and pharmaceutical research
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Specificații

ISBN-13: 9780128154113
ISBN-10: 012815411X
Pagini: 216
Dimensiuni: 152 x 229 x 17 mm
Greutate: 0.3 kg
Editura: ELSEVIER SCIENCE

Public țintă

Researchers in academia and industry working in the area of oxygen containing heterocycles, transition metal catalysis, synthetic methodologies, medicinal / pharmaceutical / natural product chemistry and drug discovery. Secondary audience of undergraduate and graduate students taking courses in heterocyclic, medicinal chemistry and organic synthesis

Cuprins

1. Introduction: The diverse aromatic δ lactones2. Natural products: A major source of isocoumarins3. Bioactive isocoumarins: their role in pharmaceutical research4. Synthesis of isocoumarins: traditional and transition metal catalyzed methods5. Preparation of Thienopyranones6. Synthesis of seleno and telluro isocoumarins7. Synthesis of a-pyranone fused with nitrogen containing heterocycles8. Synthesis of phosphaisocoumarins9. Synthesis of nature’s isocoumarins10. Synthesis of isocoumarins of pharmacological interest11. Isocoumarins in organic synthesis: Synthetic applications12. Conclusions