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Molecular Evolutionary Models in Drug Discovery

Autor Juan Bueno
en Limba Engleză Paperback – 23 ian 2020
Molecular Evolutionary Models in Drug Discovery explores the application of evolutionary molecular models in drug discovery in which secondary metabolites play a fundamental role. Secondary metabolites are not produced in isolation, they are the result of the interaction of genes, metabolism and the environment. The book examines the role of secondary metabolites as leads in drug discovery and on the development of a rational bioprospecting model for new medicines based on the evolution of secondary metabolism. These evolutionary models are part of biological systems and are the most reliable expression of the functioning of living beings.


  • Examines the integration and application of evolutionary models in the pharmaceutical industry to create new drug development platforms
  • Investigates the biotechnological prospecting of secondary metabolites and their potential use in the discovery of new drugs
  • Evaluates the ecosystem of living beings and how its molecular adaptation might improve the success of therapies
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Specificații

ISBN-13: 9780128176139
ISBN-10: 012817613X
Pagini: 192
Ilustrații: 40 illustrations (14 in full color)
Dimensiuni: 152 x 229 mm
Editura: ELSEVIER SCIENCE

Public țintă

Pharmaceutical scientists; pharmacologists, researchers, biologists, medical microbiologists, bioprospectors, biodiversity researchers, biochemists, pharmacists, and clinicians, and those who are interested in drug discovery; R&D of the preclinical drug development

Cuprins

1. Introduction2. Molecular Autopoiesis3. Natural products and molecular networks4. Symbiogenesis autopoietic5. Metabolomic autopoiesis6. Clinical outcome and autopoiesis7. Toxical autopoiesis8. Future Research and Applications