In this issue of Veterinary Clinics of North America: Equine Practice, guest editors Drs. Erica McKenzie and Stephanie Valberg bring their considerable expertise to the topic of Muscle Disorders of Horses. Top experts in the field discuss all major equine muscle disorders, covering the current state of knowledge about their pathophysiology, diagnosis, management, and treatment. This issue is authored by global experts in these topics, representing a rare collation of their collective expertise.